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| | Urease-IN-16 Basic information |
| Product Name: | Urease-IN-16 | | Synonyms: | Urease-IN-16;5-Pyrimidinecarboxylic acid, 4-(3-boronophenyl)-1,2,3,4-tetrahydro-6-methyl-2-thioxo-, 5-ethyl ester | | CAS: | 1203704-26-0 | | MF: | C14H17BN2O4S | | MW: | 320.17 | | EINECS: | | | Product Categories: | | | Mol File: | 1203704-26-0.mol |  |
| | Urease-IN-16 Chemical Properties |
| Melting point | 170-172 °C | | Boiling point | 503.251±60.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.355±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 8.192±0.10(predicted) |
| | Urease-IN-16 Usage And Synthesis |
| Uses | Urease-IN-16 (compound 4e) is a urease inhibitor, with an IC50 value of 132 μmol/L. Urease-IN-16 can coordinate with the nickel atom through the oxygen atoms of carbonyl or boronic acid groups. Urease-IN-16 shows great potential as an additive in the development of efficient fertilizers and medical applications[1]. | | References | [1] Morais Costa NE, et al. Synthesis and anti-ureolitic activity of Biginelli adducts derived from formylphenyl boronic acids. Bioorg Chem. 2024 Nov;152:107735. DOI:10.1016/j.bioorg.2024.107735 |
| | Urease-IN-16 Preparation Products And Raw materials |
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