- Anamorelin
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2025-11-02
- CAS:249921-19-5
- Min. Order:
- Purity: 0.99
- Supply Ability:
- Anamorelin
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- $15.00 / 1KG
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2021-07-13
- CAS:249921-19-5
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- Anamorelin
-
- $15.00 / 1KG
-
2021-07-09
- CAS:249921-19-5
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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| | Anamorelin Basic information |
| Product Name: | Anamorelin | | Synonyms: | anamorelin;(3R)-1-(2-Methylalanyl-D-tryptophyl)-3-(phenylmethyl)-3-piperidinecarboxylic acid 1,2,2-trimethylhydrazide;3-Piperidinecarboxylic acid, 1-(2-methylalanyl-D-tryptophyl)-3-(phenylmethyl)-, trimethylhydrazide, (3R)-;Rc 1291;Unii-dd5rba1nkf;ONO-7643;Anamorelin (RC-1291);(R)-1-((S)-2-((1H-indol-3-yl)methyl)-5-amino-5-methyl-4-oxohexanoyl)-3-benzyl-N,N',N'-trimethylpiperidine-3-carbohydrazide | | CAS: | 249921-19-5 | | MF: | C31H42N6O3 | | MW: | 546.7 | | EINECS: | | | Product Categories: | | | Mol File: | 249921-19-5.mol |  |
| | Anamorelin Chemical Properties |
| Melting point | 132-134°C | | density | 1.214 | | storage temp. | Refrigerator | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 16.22±0.46(Predicted) | | color | White to Off-White |
| | Anamorelin Usage And Synthesis |
| Uses | Anamorelin functions as a novel therapeutic options for cachexia and sarcopenia. Cancer cachexia and clinical therapeutic interventions. | | Biological Activity | Anamorelin is a non-peptidic ghrelin mimetic and growth hormone (GH) secretagogue. It is an orally-active, brain-penetrant, selective agonist of the ghrelin/growth hormone secretagogue receptor (GHSR). Anamorelin has been shown to increases appetite, overall body weight, lean body mass, and muscle strength in clinical studies with cancer patients suffering from cachexia. | | in vivo | In rats, Anamorelin (ANAM) at an oral dose of 3, 10, or 30 mg/kg once daily significantly increases both food intake and body weight from Day 2 to Day 7 of treatment compared with the vehicle control. The cumulative change in food intake and weight gain increases dose-dependently, and these changes are significant at all dose levels (P<0.05) compared to the control. Administration of Anamorelin at a single oral dose of 3, 10, or 30 mg/kg induces a dose-dependent increase in plasma GH levels and GH AUC0-6h in rats[1]. |
| | Anamorelin Preparation Products And Raw materials |
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