2-Benzylamino-2-methyl-1-propanol manufacturers
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| | 2-Benzylamino-2-methyl-1-propanol Basic information | | Uses |
| | 2-Benzylamino-2-methyl-1-propanol Chemical Properties |
| Melting point | 68-70℃ | | Boiling point | 300.8±17.0 °C(Predicted) | | density | 1.006±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C(protect from light) | | solubility | Chloroform, DMSO, Methanol | | form | Solid | | pka | 14.55±0.10(Predicted) | | color | Off-White | | InChI | InChI=1S/C11H17NO/c1-11(2,9-13)12-8-10-6-4-3-5-7-10/h3-7,12-13H,8-9H2,1-2H3 | | InChIKey | JIDHEIXSIHNMCG-UHFFFAOYSA-N | | SMILES | C(O)C(C)(NCC1=CC=CC=C1)C | | CAS DataBase Reference | 10250-27-8 |
| | 2-Benzylamino-2-methyl-1-propanol Usage And Synthesis |
| Uses | 2-Benzylamino-2-methyl-1-propanol, as a basic skeleton, is commonly used as an organic ligand in the structural modification and synthesis of oxazoline ligands. These ligands have wide applications in coordination chemistry and organometallic chemistry, playing a particularly important role in catalytic reactions. As a fundamental skeleton in organic synthesis, this molecule is frequently used in basic organic chemistry research to explore new reaction pathways, catalyst design, and synthetic methods for novel organic ligands. | | Chemical Properties | Yellow-Orange Solid | | Synthesis Reference(s) | Tetrahedron, 44, p. 6801, 1988 DOI: 10.1016/S0040-4020(01)86206-2 | | Synthesis | To a solution of 2-amino-2-methylpropan-1-ol (1 g, 11.22 mmol) and benzaldehyde (1.310 g, 12.34 mmol) in DCE (15 mL) at RT was added portionwise sodium triacetoxyborohydride (6.66 g, 31.4 mmol), and the mixture was stirred for 3 h. The mixture was diluted with EtOAc and washed with saturated aqueous NaHCO3. The organic layer was dried over MgSO4, filtered, and concentrated. The crude product 2-Benzylamino-2-methyl-1-propanol (1.247 g, 6.96 mmol, 62 % yield) was used without further purification. LCMS (m/z): 180.0 (M+H+). |
| | 2-Benzylamino-2-methyl-1-propanol Preparation Products And Raw materials |
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