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| | 2',6'-DIMETHYLACETANILIDE Basic information |
| Product Name: | 2',6'-DIMETHYLACETANILIDE | | Synonyms: | N-ACETYL-2,6-XYLIDINE;N-(2,6-DIMETHYL-PHENYL)-ACETAMIDE;TIMTEC-BB SBB008144;ALPHA,2',6'-DIMETHYLACETANILIDE;2',6'-DIMETHYLACETANILIDE;2,6-DIMETHYLACETANILIDE;2',6'-ACETOXYLIDIDE;2,6-Acetoxylide | | CAS: | 2198-53-0 | | MF: | C10H13NO | | MW: | 163.22 | | EINECS: | 218-596-8 | | Product Categories: | Anilines, Amides & Amines;Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;1 | | Mol File: | 2198-53-0.mol |  |
| | 2',6'-DIMETHYLACETANILIDE Chemical Properties |
| Melting point | 182-184 °C(lit.) | | Boiling point | 290.31°C (rough estimate) | | density | 1.052 | | refractive index | 1.5400 (estimate) | | storage temp. | 2-8°C | | solubility | Chloroform (Slightly), Methanol (Slightly) | | pka | 15.14±0.70(Predicted) | | form | Solid | | color | Crystals | | InChI | 1S/C10H13NO/c1-7-5-4-6-8(2)10(7)11-9(3)12/h4-6H,1-3H3,(H,11,12) | | InChIKey | NRPTXWYBRKRZES-UHFFFAOYSA-N | | SMILES | CC(=O)Nc1c(C)cccc1C | | CAS DataBase Reference | 2198-53-0(CAS DataBase Reference) | | EPA Substance Registry System | Acetamide, N-(2,6-dimethylphenyl)- (2198-53-0) |
| Hazard Codes | Xn | | Risk Statements | 20/21/22-36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | RTECS | AN7470000 | | TSCA | TSCA listed | | HS Code | 29242990 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 | | Toxicity | LD50 orl-mus: 620 mg/kg TXAPA9 19,20,71 |
| | 2',6'-DIMETHYLACETANILIDE Usage And Synthesis |
| Chemical Properties | off-white to yellow cryst. needles or cryst.powder | | Uses | Lidocaine (L397800) impurity. | | Synthesis Reference(s) | Journal of the American Chemical Society, 106, p. 5759, 1984 DOI: 10.1021/ja00331a073
Chemical and Pharmaceutical Bulletin, 30, p. 4242, 1982 DOI: 10.1248/cpb.30.4242
Journal of Heterocyclic Chemistry, 2, p. 181, 1965 DOI: 10.1002/jhet.5570020214 | | General Description | 2,6-Dimethylacetanilide undergoes iodination by electrophylic substitution reaction of chloroacetanilide, in the presence of ferroiodide and copperchloride as catalyst, to form 4-iodine-2,6-dimethylacetanilide. | | Safety Profile | Moderately toxic by ingestion.When heated to decomposition it emits toxic fumes ofNOx. |
| | 2',6'-DIMETHYLACETANILIDE Preparation Products And Raw materials |
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