| Company Name: |
Alfa Aesar |
| Tel: |
400-6106006 |
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- ：1-Benzylimidazole
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- $1.00
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2026-08-07
- CAS:4238-71-5
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 100000KG
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| | 1-Benzylimidazole Basic information |
| | 1-Benzylimidazole Chemical Properties |
| Melting point | 68-70 °C(lit.) | | Boiling point | 310 °C(lit.) | | density | 1.2419 (rough estimate) | | refractive index | 1.6392 (estimate) | | storage temp. | Sealed in dry,Room Temperature | | solubility | DMF: >530 μg/ml; DMSO: >560 μg/ml; Ethanol: >500 μg/ml; PBS pH 7.2: >6.5 mg/ml | | pka | 6.79±0.10(Predicted) | | form | Crystals | | color | Brownish | | Water Solubility | insoluble | | λmax | 215nm(EtOH)(lit.) | | BRN | 114571 | | InChI | 1S/C10H10N2/c1-2-4-10(5-3-1)8-12-7-6-11-9-12/h1-7,9H,8H2 | | InChIKey | KKKDZZRICRFGSD-UHFFFAOYSA-N | | SMILES | C(c1ccccc1)n2ccnc2 | | CAS DataBase Reference | 4238-71-5(CAS DataBase Reference) | | NIST Chemistry Reference | 1H-Imidazole, 1-(phenylmethyl)-(4238-71-5) |
| Risk Statements | 36/37/38 | | Safety Statements | 22-24/25 | | WGK Germany | 3 | | F | 10 | | HS Code | 29332900 | | Storage Class | 11 - Combustible Solids |
| | 1-Benzylimidazole Usage And Synthesis |
| Chemical Properties | BROWNISH CRYSTALS | | Uses | 1-Benzylimidazole acts as an inducer of various cytochrome P-450 isozymes and inhibitor of thromboxane A2 synthase. 1-Benzylimidazole has been used to prepare cyclodextrin-ionic liquid polymer (βCD-BIMOTs-TDI) | | Uses | Sodium thiosulfate pentahydrate may be involved in the estimation of iodide in pharmaceutical samples, using spectrophotometric method. | | Synthesis Reference(s) | Journal of the American Chemical Society, 71, p. 383, 1949 DOI: 10.1021/ja01170a002 | | General Description | 1-Benzylimidazole has been used to prepare cyclodextrin-ionic liquid polymer (βCD-BIMOTs-TDI). | | Biochem/physiol Actions | 1-Benzylimidazole is a CYP inhibitor that inhibits the biotransformation of MeO-BDEs (methoxylated-brominated diphenyl ethers) to OH-BDEs (hydroxylated) in fishes. | | Synthesis | First, 8.35g concentration of 36% formaldehyde aqueous solution and 18.1g concentration of 32% glyoxal aqueous solution was added to 250mL three-necked flask, stirring and heating to 50 reflux, and then 6.05g concentration of 28% of ammonia and benzylamine methanol solution (dosage of 10.7g of benzylamine dissolved in 50mL methanol) was added to the three-necked flask drop by drop, add the end of the reaction continue to reflux 4h, evaporated methanol, poured into ice water, extracted with ethyl acetate, and then concentrated by rotary evaporation at 40 , and then vacuum dried at 60 for 24h to obtain light yellow N-benzyl imidazole solid, the yield was about 75%. |
| | 1-Benzylimidazole Preparation Products And Raw materials |
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