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| | Fmoc-2,2,6,6-tetramethylpiperidine-N-oxyl-4-amino-4-carboxylic acid Basic information |
| Product Name: | Fmoc-2,2,6,6-tetramethylpiperidine-N-oxyl-4-amino-4-carboxylic acid | | Synonyms: | Fmoc-2,2,6,6-tetramethylpiperidine-N-oxyl-4-amino-4-carboxylic acid≥ 98% (HPLC);FMOC-TOAC;FMOC-TOAC-OH 100 MG;FMOC-TOAC-OH 500 MG;4-(9H-fluoren-9-ylmethoxycarbonylamino)-2,2,6,6-tetramethyl-1-oxidopiperidin-1-ium-4-carboxylic acid;1-Piperidinyloxy,4-carboxy-4-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-2,2,6,6-tetramethyl-;Fmoc-2,2,6,6-tetramethylpiperidine-N-oxyl-4-amino-4-carboxylic acid | | CAS: | 93372-25-9 | | MF: | C25H29N2O5* | | MW: | 437.51 | | EINECS: | | | Product Categories: | Chiral Reagents;Spin Labeling Compounds | | Mol File: | Mol File |  |
| | Fmoc-2,2,6,6-tetramethylpiperidine-N-oxyl-4-amino-4-carboxylic acid Chemical Properties |
| Melting point | 162-164°C | | storage temp. | Store at +2°C to +8°C. | | solubility | Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly) | | form | Solid | | color | Pale Yellow to Yellow | | Major Application | peptide synthesis | | InChI | 1S/C25H29N2O5/c1-23(2)14-25(21(28)29,15-24(3,4)27(23)31)26-22(30)32-13-20-18-11-7-5-9-16(18)17-10-6-8-12-19(17)20/h5-12,20H,13-15H2,1-4H3,(H,26,30)(H,28,29) | | InChIKey | FAQWDTRJLKQJBN-UHFFFAOYSA-N |
| WGK Germany | WGK 2 water endangering | | HS Code | 2933 39 99 | | Storage Class | 11 - Combustible Solids |
| | Fmoc-2,2,6,6-tetramethylpiperidine-N-oxyl-4-amino-4-carboxylic acid Usage And Synthesis |
| Chemical Properties | Yellow Solid | | Uses | Fmoc-2,2,6,6-tetramethylpiperidine-N-oxyl-4-amino-4-carboxylic Acid is a stable, free radical spin label. | | Uses | A stable free radical spin label. | | Uses | A protected spin-labelled, cyclic, chiral amino acid resolved in an enantiomerically pure state | | General Description | Fmoc-TOAC-OH is a useful tool for the incorporation of the ESR spin-label TOAC into peptide sequences [1]. Incorporation of this derivative and the following residue is best achieved using HATU activation. TFA/water/TIS should be used for cleavage of TOAC-containing peptides. The use of EDT should be avoided as it can cause permanent reduction of the nitroxide radical [2]. Following cleavage, the TOAC peptide should be treated with aqueous ammonia in air to regenerate the nitroxide from the hydroxylamine that is generated by the TFA treatment. | | reaction suitability | reaction type: Fmoc solid-phase peptide synthesis |
| | Fmoc-2,2,6,6-tetramethylpiperidine-N-oxyl-4-amino-4-carboxylic acid Preparation Products And Raw materials |
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