| Company Name: |
GL Biochem (Shanghai) Ltd
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| Tel: |
21-61263452 13641803416 |
| Email: |
ymbetter@glbiochem.com |
| Products Intro: |
Product Name:Somatostatin 14, acetate;AGCKNFFWKTFTSC(Disulfidebridge:3-14),acetatesalt
Purity:95% HPLC 98% HPLC Package:1mg,5mg,10mg,25mg,100mg,1g,10g
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| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:Somatostatin monoacetate
CAS:54472-66-1
Purity:98% Remarks:Reach out to us for more information about custom solutions.
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AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT manufacturers
- Compound TP1035L(SC)
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- $50.00 / 1mg
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2025-09-16
- CAS:54472-66-1
- Min. Order:
- Purity: 100.00%
- Supply Ability: 10g
- Somatostatin Acetate
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- $0.00 / 1BOX
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2025-02-17
- CAS:54472-66-1
- Min. Order: 1BOX
- Purity: 99%
- Supply Ability: 20T
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| | AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT Basic information |
| Product Name: | AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT | | Synonyms: | H-ALA-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS-OH (DISULFIDE BRIDGE: 3-14), ACETATE SALT;AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT;SOMATOSTATIN 14, ACETATE;Somatostatin monoacetate;GHIH;Somatostatin (sheep), monoacetate (salt);Somatostatin-14 (human, mouse, rat, porcine, bovine, ovine) (acetate);Cyclic somatostatin Acetate | | CAS: | 54472-66-1 | | MF: | C78H108N18O21S2 | | MW: | 1697.95 | | EINECS: | | | Product Categories: | peptide | | Mol File: | Mol File |  |
| | AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Water: 0.3 mg/ml | | form | A powder |
| | AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT Usage And Synthesis |
| Description | Somatostatin-14 is a natural cyclic peptide hormone derived from the preprohormone, somatostatin. It is a somatostatin (SST) receptor agonist that binds to SST1, SST2, SST3, SST4, and SST5 (IC50s = 0.22, 0.10, 0.28, 1.23, and 0.30 nM, respectively, in CCL39 cells expressing human recombinant receptors). It inhibits cAMP accumulation induced by forskolin in CCL39 cells expressing human recombinant SST1, SST2, SST3, SST4, and SST5 (EC50s = 6.16, 4.37, 17.38, 2.95, and 4.67 nM, respectively). Somatostatin-14 inhibits the release of growth hormone, prolactin, thyrotropin, glucagon, and insulin, as well as other signaling molecules. | | References | [1] D J HADJIDAKIS. Differences between somatostatin-28 and somatostatin-14 with respect to their biological effects in healthy humans and acromegalics.[J]. Clinical physiology and biochemistry, 1986, 4 6: 372-383.
[2] S SIEHLER D H K Seuwen. Characterisation of human recombinant somatostatin receptors. 1. Radioligand binding studies.[J]. Naunyn-Schmiedeberg’s archives of pharmacology, 1999, 360 5: 488-499. DOI: 10.1007/s002109900141
[3] S SIEHLER D H. Characterisation of human recombinant somatostatin receptors. 3. Modulation of adenylate cyclase activity.[J]. Naunyn-Schmiedeberg’s archives of pharmacology, 1999, 360 5: 510-521. DOI: 10.1007/s002109900143
[4] GILLIES G. Somatostatin: the neuroendocrine story.[J]. Trends in pharmacological sciences, 1997, 18 3: 87-95. DOI: 10.1016/s0165-6147(96)01032-2
[5] IAN M P JOSEPH. A model for integrative study of human gastric acid secretion.[J]. Journal of applied physiology, 2003, 94 4: 1602-1618. DOI: 10.1152/japplphysiol.00281.2002 |
| | AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT Preparation Products And Raw materials |
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