Cletoquine Oxalate

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Company Name: J & K SCIENTIFIC LTD.  
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Cletoquine Oxalate manufacturers
Cletoquine Oxalate Basic information
Product Name:Cletoquine Oxalate
Synonyms:(+/-)-Desethylhydroxychloroquine Oxalate;2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]amino]ethanol Oxalate;Cletoquine Oxalate
CAS:14142-64-4
MF:C18H24ClN3O5
MW:397.85326
EINECS:
Product Categories:Heterocycles;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:14142-64-4.mol
Cletoquine Oxalate Structure
Cletoquine Oxalate Chemical Properties
Melting point >115°C (dec.)
storage temp. Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility DMSO (Slightly, Heated), Methanol (Slightly)
form Solid
color Pale Yellow to Yellow
Stability:Hygroscopic
CAS DataBase Reference14142-64-4
Safety Information
MSDS Information
Cletoquine Oxalate Usage And Synthesis
Chemical PropertiesBrown Solid
UsesCletoquine Oxalate is a metabolite of Hydroxychloroquine.
in vivo

Hydroxychloroquine (5 mg/kg intravenously) is administered to BALB/c mice for blood and tissue to determine the content of Cletoquine (Desethylhydroxychloroquine). The tissue to blood concentration ratio (Kp) is ≥1, indicating accumulation of Cletoquine in tissues. The Cletoquine Kp ratio for the various tissues are observed in the descending order of liver (114.3)>kidney (24.4)>spleen (19.3)>lungs (16.5)>heart (5.5)[3].

IC 50Plasmodium
Cletoquine Oxalate Preparation Products And Raw materials
Tag:Cletoquine Oxalate(14142-64-4) Related Product Information
Ferrous sulfate Quinolinic acid Chloroquine diphosphate Hydroxychloroquine sulfate HA/HEMAGGLUTININ protein, INFLUENZA B (ACN29380, SF9) HA/Hemagglutinin Protein, H12N1 (ABB88099, sf9, His)