O-PHOSPHO-L-THREONINE

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Products Intro: Product Name:O-PHOSPHO-L-THREONINE
CAS:1114-81-4
Purity:98.0% Package:1KG;0.1USD
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Products Intro: Product Name:O-PHOSPHO-L-THREONINE
CAS:1114-81-4
Purity:98% Package:5KG;1KG
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CAS:1114-81-4
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Products Intro: Product Name:O-Phospho-L-Threonine
CAS:1114-81-4
Purity:0.98 Package:25kg;1kg
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Products Intro: Product Name:O-Phospho-L-Threonine
CAS:1114-81-4
Purity:98% Min. Package:5KG;1KG

O-PHOSPHO-L-THREONINE manufacturers

O-PHOSPHO-L-THREONINE Basic information
Product Name:O-PHOSPHO-L-THREONINE
Synonyms:L-THREONINE O-PHOSPHATE;L-2-AMINO-3-HYDROXYBUTANOIC ACID 3-PHOSPHATE;H-THR(PO3H2)-OH;(s)-2-amino-3-hydroxybutanoic acid 3-phosphate;L-Threonine O-phosphate, (S)-2-Amino-3-hydroxybutanoic acid 3-phosphate;(2S,3R)-2-Amino-3-phosphonooxybutanoic acid;L-Threonine dihydrogen phosphate;O-Phosphothreonine
CAS:1114-81-4
MF:C4H10NO6P
MW:199.1
EINECS:214-217-5
Product Categories:
Mol File:1114-81-4.mol
O-PHOSPHO-L-THREONINE Structure
O-PHOSPHO-L-THREONINE Chemical Properties
Melting point 169 °C
Boiling point 454.0±55.0 °C(Predicted)
density 1.671±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility NH4OH 1 M: 0.1 g/mL, clear, colorless
pka1.73±0.10(Predicted)
form A solid
color white
Optical Rotation-9.7°(C=0.01g/mI, H2O, 20°C, 589nm)
BRN 1727078
InChI1S/C4H10NO6P/c1-2(3(5)4(6)7)11-12(8,9)10/h2-3H,5H2,1H3,(H,6,7)(H2,8,9,10)/t2-,3+/m1/s1
InChIKeyUSRGIUJOYOXOQJ-GBXIJSLDSA-N
SMILESC[C@@H](OP(O)(O)=O)[C@H](N)C(O)=O
Safety Information
WGK Germany 3
10
Storage Class11 - Combustible Solids
MSDS Information
ProviderLanguage
SigmaAldrich English
O-PHOSPHO-L-THREONINE Usage And Synthesis
UsesO-Phospho-L-threonine is a threonine derivative[1].
DefinitionChEBI: O-phospho-L-threonine is a L-threonine derivative phosphorylated at the side-chain hydroxy function. It has a role as an Escherichia coli metabolite. It is a L-threonine derivative, a non-proteinogenic L-alpha-amino acid and an O-phosphoamino acid. It is a conjugate acid of an O-phosphonato-L-threonine(2-).
Biochem/physiol ActionsO-Phospho-L-threonine is an amino acid derivative.
IC 50Human Endogenous Metabolite
Purification MethodsDissolve the phosphate in the minimum volume of H2O, add charcoal, stir for a few minutes, filter and apply onto a column of Dowex 50W (H+ form), then elute with 2N HCl. Evaporate the eluates under reduced pressure whereby the desired fraction produces crystals of the phosphate which can be recrystallised from H2O/MeOH mixtures and the crystals are then dried in vacuo over P2O5 at ~80o. [de Verdier Acta Chem Scand 7 196 1953, Beilstein 4 IV 3175.]
References[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. DOI:10.1080/10408398.2012.708368
O-PHOSPHO-L-THREONINE Preparation Products And Raw materials
Raw materialsL-Threonine
Tag:O-PHOSPHO-L-THREONINE(1114-81-4) Related Product Information
3-Hydroxybutyric acid FMOC-THR(PO3H2)-OH O-PHOSPHO-DL-THREONINE O-PHOSPHO-L-THREONINE-AGAROSE THREONINE PHOSPHATE, L-, [14C(U)] FMOC-THR(PO3ME2)-OH Fmoc-O-(benzylphospho)-L-threonine O-PHOSPHO-L-THREONINE