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4-Methoxyfuro[2,3-b]quinolin-8-ol

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Products Intro: Product Name:4-Methoxyfuro[2,3-b]quinolin-8-ol
CAS:2255-50-7
Purity:HPLC>=98% Package:5mg
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Products Intro: Product Name:8-hydroxy dictanmnine
CAS:2255-50-7
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CAS:2255-50-7
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Products Intro: Product Name:8-Hydroxy dictanmnine
CAS:2255-50-7
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4-Methoxyfuro[2,3-b]quinolin-8-ol manufacturers

  • Robustine
  • Robustine pictures
  • $73.00 / 1mg
  • 2026-05-25
  • CAS:2255-50-7
  • Min. Order:
  • Purity: 99.97%
  • Supply Ability: 10g
  • Robustine
  • Robustine pictures
  • $3500.00 / 1g
  • 2024-11-28
  • CAS:2255-50-7
  • Min. Order: 1g
  • Purity: 98
  • Supply Ability: 50 Kg
4-Methoxyfuro[2,3-b]quinolin-8-ol Basic information
Product Name:4-Methoxyfuro[2,3-b]quinolin-8-ol
Synonyms:4-Methoxyfuro[2,3-b]quinolin-8-ol;Robustine;8-Hydroxydictamnine;NPLC 0314;Robustine (Haplophyllum);8-hydroxy dictanmnine;Furo[2,3-b]quinolin-8-ol, 4-methoxy-;alkaloid,phosphodiesterase,Phosphodiesterase (PDE),Robustine,PDE5A,inhibit,Inhibitor
CAS:2255-50-7
MF:C12H9NO3
MW:215.2
EINECS:
Product Categories:Alkaloids
Mol File:2255-50-7.mol
4-Methoxyfuro[2,3-b]quinolin-8-ol Structure
4-Methoxyfuro[2,3-b]quinolin-8-ol Chemical Properties
Melting point 148-149℃ (ethanol )
Boiling point 411.9±40.0 °C(Predicted)
density 1.378±0.06 g/cm3(Predicted)
storage temp. 4°C, protect from light
pka5.34±0.30(Predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
4-Methoxyfuro[2,3-b]quinolin-8-ol Usage And Synthesis
DescriptionHaplophyllum robustum Bge. yields this alkaloid which forms colourless crystals from EtOH. It forms a series of crystalline salts and derivatives including the hydrochloride, m.p. 199-200°C; picrate, m.p. I 79-180°C; acetyl derivative, m.p.174-5°C; methyl derivative, m.p. 140-2°C and the tetrahydrG compound with m.p.201-2°C.
UsesRobustine, a furoquinoline alkaloid, from Dictamnus albus, exhibits inhibitory potency against human phosphodiesterase 5 (hPDE5A) in vitro[1].
DefinitionChEBI: A quinoline alkaloid that is furo[2,3-b]quinoline substituted by a methoxy and a hydroxy group at positions 4 and 8 respectively.
IC 50PDE5A
ReferencesFakhritdinova, Sidyakin, Yunusov,Khim. Prir.Soedin., 1, 107 (1965)
Faizutdinova, Yunusov, ibid, 3, 260 (1967)
Narasimhan, Paradkar, Alurkar, Tetrahedron, 27,1351 (1971)
4-Methoxyfuro[2,3-b]quinolin-8-ol Preparation Products And Raw materials
Tag:4-Methoxyfuro[2,3-b]quinolin-8-ol(2255-50-7) Related Product Information
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