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| | METHYL 5-METHYLPYRAZINE-2-CARBOXYLATE Basic information |
| | METHYL 5-METHYLPYRAZINE-2-CARBOXYLATE Chemical Properties |
| Melting point | 92 °C | | Boiling point | 234.1±35.0 °C(Predicted) | | density | 1.169±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | Dichloromethane, Methanol | | pka | -0.23±0.10(Predicted) | | form | Solid | | Appearance | Light yellow to yellow Solid | | InChI | InChI=1S/C7H8N2O2/c1-5-3-9-6(4-8-5)7(10)11-2/h3-4H,1-2H3 | | InChIKey | CRBOSZMVDHYLJE-UHFFFAOYSA-N | | SMILES | C1(C(OC)=O)=NC=C(C)N=C1 |
| | METHYL 5-METHYLPYRAZINE-2-CARBOXYLATE Usage And Synthesis |
| Uses | Methyl 5-methylpyrazine-2-carboxylate is an intermediate in the synthesis of 4-[β-(5-Methylpyrazinyl-2-carboxamido)ethyl]benzene Sulfonamide which itself is an intermediate in the synthesis of Glipizide (G410225). | | References | [1] Patent: US2005/239803, 2005, A1. Location in patent: Page/Page column 2
[2] Patent: US2005/261312, 2005, A1. Location in patent: Page/Page column 2
[3] European Journal of Organic Chemistry, 2010, # 14, p. 2687 - 2695
[4] Patent: WO2018/78657, 2018, A1. Location in patent: Page/Page column 19
[5] Journal of Medicinal Chemistry, 2002, vol. 45, # 18, p. 3878 - 3890 |
| | METHYL 5-METHYLPYRAZINE-2-CARBOXYLATE Preparation Products And Raw materials |
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