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| | PTH (1-31) (human) Basic information |
| Product Name: | PTH (1-31) (human) | | Synonyms: | H-SER-VAL-SER-GLU-ILE-GLN-LEU-MET-HIS-ASN-LEU-GLY-LYS-HIS-LEU-ASN-SER-MET-GLU-ARG-VAL-GLU-TRP-LEU-ARG-LYS-LYS-LEU-GLN-ASP-VAL-OH;PARATHYROID HORMONE (1-31) (HUMAN);Human PTH-(1-31);PTH (1-31) (human) | | CAS: | 157938-23-3 | | MF: | C162H269N49O47S2 | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![PTH (1-31) (human) Structure]() |
| | PTH (1-31) (human) Chemical Properties |
| storage temp. | -15°C | | Sequence | Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val |
| | PTH (1-31) (human) Usage And Synthesis |
| Uses | Human PTH-(1-31) is the 1-31 fragment of human PTH. Human PTH-(1-31) stimulates the release of cAMP and also is a weaker stimulator of the 25-hydroxyvitamin D-1α-hydroxylase. Human PTH-(1-31) induces bone formation without inducing bone resorption. Human PTH-(1-31) has the potential for the research of osteoporosis[1][2]. | | References | [1] Fraher LJ, et al. Comparison of the biochemical responses to human parathyroid hormone-(1-31)NH2 and hPTH-(1-34) in healthy humans. J Clin Endocrinol Metab. 1999 Aug;84(8):2739-43. DOI:10.1210/jcem.84.8.5891
[2] K. Henriksen, et al. Evaluation of the efficacy, safety and pharmacokinetic profile of oral recombinant human parathyroid hormone [rhPTH(1-31)NH2] in postmenopausal women with osteoporosis. Bone. 2013, 53 (1): 160-166. |
| | PTH (1-31) (human) Preparation Products And Raw materials |
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