DMT-2'-O-MOE-rU Phosphoramidite manufacturers
- 2'-O-MOE-U
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2026-04-21
- CAS:163759-97-5
- Purity:
- Supply Ability: 10g
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| | DMT-2'-O-MOE-rU Phosphoramidite Basic information |
| Product Name: | DMT-2'-O-MOE-rU Phosphoramidite | | Synonyms: | (2R,3R,4R,5R)-2-((BIS(4-METHOXYPHENYL)(PHENYL)METHOXY)METHYL)-5-(2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)-4-(2-METHOXYETHOXY)TETRAHYDROFURAN-3-YL 2-CYANOETHYL DIISOPROPYLPHOSPHORAMIDITE;5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)uridine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite];5'-O-DMTr-2'-O-(2-methoxyethyl)-uridine-3'-CED-phosphoramidite;5'-O-DMT-2'-O-(2-methoxyethyl)uridine 3'-CE phosphoramidite;2'-O-MOE-U-CE Phosphoramidite;2'-O-MOE-U-3'-phosphoramidite;2'-O-MOE-U Phosphoramidite;Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI) | | CAS: | 163759-97-5 | | MF: | C42H53N4O10P | | MW: | 804.86 | | EINECS: | | | Product Categories: | Phosphoramidite | | Mol File: | 163759-97-5.mol |  |
| | DMT-2'-O-MOE-rU Phosphoramidite Chemical Properties |
| storage temp. | 4°C, protect from light | | pka | 9.39±0.10(Predicted) | | form | Solid | | color | White to off-white | | InChIKey | ZLOKLUONKGURQI-LWTSSKLSNA-N | | SMILES | O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@H](OCCOC)[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,36,42,r| |
| | DMT-2'-O-MOE-rU Phosphoramidite Usage And Synthesis |
| Description | 2'-O-MOE-U-3'-phosphoramidite (DMT-2'-O-MOE-rU Phosphoramidite) is a 2'-O-MOE-protected nucleoside phosphoramidite that can be inserted into oligonucleotide phosphoramidites for antisense RNA. The 2'-MOE backbone enhances stability, resists nuclease, and exhibits low toxicity for improved genetic manipulation. | | Chemical Properties | White to Light yellow powder to crystal | | Uses | 2'-O-MOE-U is a phosphoramidite, can be used for oligonucleotide synthesis[1]. | | References | [1] Lyu F, et al. A 2'-modified uridine analog, 2'-O-(methylthiomethoxy)methyl uridine, for siRNA applications. Bioorg Med Chem Lett. 2022 Oct 15;74:128939. DOI:10.1016/j.bmcl.2022.128939 |
| | DMT-2'-O-MOE-rU Phosphoramidite Preparation Products And Raw materials |
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