- Pemetrexed Disodium
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- $0.00 / 25Kg/Bag
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2026-03-05
- CAS:357166-30-4
- Min. Order: 2Kg/Bag
- Purity: Medicine grade / 99% min
- Supply Ability: 20 tons
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| | Pemetrexed disodium hemipentahydrate Basic information |
| Product Name: | Pemetrexed disodium hemipentahydrate | | Synonyms: | N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid disodium salt hydrate;PeMetrexed sodiuM hydrate (1:2:2.5);Pemetrexed disodium hydrate;PeMetrexed DisodiuM heMipenta hydrate;Pemetrexed disodium 2.5 hydrate;PeMetrexed (disodiuM heMipenta hydrate) (1:2:2.5);L-GlutaMic acid,N-[4-[2-(2-aMino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyriMidin-5-yl)ethyl]benzoyl]-,sodiuM salt, hydrate (2:4:5) (9CI);LY-231514 Disodium Hydrate | | CAS: | 357166-30-4 | | MF: | C20H24N5NaO7 | | MW: | 469.43 | | EINECS: | 814-356-7 | | Product Categories: | Inhibitors;Anti-cancer&immunity;API;357166-30-4 | | Mol File: | 357166-30-4.mol |  |
| | Pemetrexed disodium hemipentahydrate Chemical Properties |
| Melting point | 274-276°C (dec.) | | storage temp. | Room Temperature | | solubility | DMSO, Methanol, Water | | form | Solid | | color | Off-White | | InChIKey | AEZRDYKQLPDYEH-YTCXBBKHNA-N | | SMILES | C(C1=CNC2NC(N)=NC(=O)C1=2)CC1C=CC(C(=O)N[C@H](C(=O)O)CCC(=O)O)=CC=1.[NaH].O |&1:20,r| | | CAS DataBase Reference | 357166-30-4(CAS DataBase Reference) |
| WGK Germany | WGK 3 | | Storage Class | 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | | Hazard Classifications | Eye Irrit. 2
Muta. 2
Repr. 1A
Skin Irrit. 2
STOT RE 1 |
| | Pemetrexed disodium hemipentahydrate Usage And Synthesis |
| Uses | Pemetrexed Disodium Hydrate is an chemotherapy drug for the treatment of pleural mesothelioma and non-small cell lung cancer. Pemetrexed Disodium Hydrate exhibit inhibitory activities towards thymidylate synthase as well as other folate dependent enzymes. | | Brand name | Pemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the brand name Alimta. | | Mechanism of action | Pemetrexed disodium hemipentahydrate stops cells from using folic acid to make DNA and may kill cancer cells. | | in vivo | The group of mice treated with PC61 plus Pemetrexed demonstrates statistically longer survival than other groups. In a survival analysis, significantly better survival is observed in the group of mice treated with PC61 plus Pemetrexed compare with those treated with PC61 alone, rat IgG plus Pemetrexed, or no treatment. |
| | Pemetrexed disodium hemipentahydrate Preparation Products And Raw materials |
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