| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Sch 39304 CAS:120924-80-3 Package:50mg/RMB 13800;100mg/RMB 17500;25mg/RMB 10600
|
Threo-2-(2,4-difluorophenyl)-3-methylsulfonyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol manufacturers
- Sch 39304
-
- $1980.00 / 50mg
-
2026-03-12
- CAS:120924-80-3
- Min. Order:
- Purity:
- Supply Ability: 10g
|
| | Threo-2-(2,4-difluorophenyl)-3-methylsulfonyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Basic information |
| Product Name: | Threo-2-(2,4-difluorophenyl)-3-methylsulfonyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol | | Synonyms: | Aids007341;Aids-007341;Rac-(2R*,3R*)-2-(2,4-difluorophenyl)-3-(methylsulfonyl)-1-(1,2,4-triazol-1-yl)-2-butanol;1H-1,2,4-Triazole-1-ethanol, α-(2,4-difluorophenyl)-α-[(1R)-1-(methylsulfonyl)ethyl]-, (αR)-rel- | | CAS: | 120924-80-3 | | MF: | C13H15F2N3O3S | | MW: | 331.34 | | EINECS: | | | Product Categories: | | | Mol File: | 120924-80-3.mol |  |
| | Threo-2-(2,4-difluorophenyl)-3-methylsulfonyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Chemical Properties |
| Boiling point | 594.3±60.0 °C(Predicted) | | density | 1.42±0.1 g/cm3(Predicted) | | pka | 11.11±0.29(Predicted) |
| | Threo-2-(2,4-difluorophenyl)-3-methylsulfonyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Usage And Synthesis |
| Uses | SM-8668 is an effective orally active antifungal agent, with median effective doses (ED50) of 0.18, 3.7, and 5.9 mg/kg for systemic candidiasis, aspergillosis, and cryptococcosis in mice, respectively. Pharmacokinetic studies in mice and rats indicate that SM-8668 has a long half-life and a high total exposure. SM-8668 can be used in anti-infective research[1]. | | References | [1] Tanio T, et al. In vivo efficacy of SM-8668 (Sch 39304), a new oral triazole antifungal agent. Antimicrob Agents Chemother. 1990 Jun;34(6):980-4. DOI:10.1128/AAC.34.6.980 |
| | Threo-2-(2,4-difluorophenyl)-3-methylsulfonyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Preparation Products And Raw materials |
|