PU-H71 Hydrate 基本信息
| 中文名称 | PU-H71 Hydrate |
|---|---|
| 中文同义词 | 化合物 PU-H71 HYDRATE |
| 英文名称 | PU-H71 Hydrate |
| 英文同义词 | PU-H71 Hydrate;6-AMino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-Methylethyl)-9H-purine-9-propanaMine hydrate;CS-106;PU-H71 Hydrate(1:x) |
| CAS号 | 1202865-65-3 |
| 分子式 | C18H21IN6O2S |
| 分子量 | 512.36781 |
| EINECS号 | 604-604-1 |
| 相关类别 | Amines;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds |
| Mol文件 | 1202865-65-3.mol |
| 结构式 |  |
PU-H71 Hydrate 性质
| 溶解度 | DMF: 12 mg/ml DMF: PBS(pH 7.2)(1:1): 0.5 mg/ml DMSO: 10 mg/ml |
|---|
用途
PU-H71 is a potent Hsp90 inhibitor (IC50 = 50 nM). Hsp90 plays a critical role in modulating the activity of many cell signaling proteins and are an attractive target for anti-cancer therapeutics. Stu
dies indicate that Hsp90 inhibitors may serve as potential anti-Parkinson鈥瞫 disease.