| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:Ki23057
CAS:516523-31-2
Purity:98% Remarks:Reach out to us for more information about custom solutions.
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| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Ki23057
CAS:516523-31-2
Package:100mg/RMB 17500;25mg/RMB 10600;50mg/RMB 13800
|
KI23057 manufacturers
- Ki23057
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- $2500.00
-
2026-05-11
- CAS:516523-31-2
- Purity:
- Supply Ability: 10g
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| | KI23057 Basic information |
| Product Name: | KI23057 | | Synonyms: | KI23057;2-[2-[4-[4-(4-tert-butylanilino)phenoxy]-6-methoxyquinolin-7-yl]oxyethylamino]ethanol;Ethanol, 2-[[2-[[4-[4-[[4-(1,1-dimethylethyl)phenyl]amino]phenoxy]-6-methoxy-7-quinolinyl]oxy]ethyl]amino]- | | CAS: | 516523-31-2 | | MF: | C30H35N3O4 | | MW: | 501.62 | | EINECS: | | | Product Categories: | | | Mol File: | 516523-31-2.mol |  |
| | KI23057 Chemical Properties |
| | KI23057 Usage And Synthesis |
| Uses | Ki 23057 is a competitive, orally active inhibitor for tyrosine kinase, which inhibits the phosphorylation of K-samII/FGF-R2, VEGF-R1, VEGF-R2, PDGF-Rβ and c-Kit, with IC50s of 88, 69, 83, 100 and 480 nM. Ki 23057 inhibits the proliferation of sclerogastric cancer cells OCUM-2MD3 and OCUM-8, and induces apoptosis. Ki 23057 exhibits antitumor efficacy in mouse models[1]. | | References | [1] Nakamura K, et al., A novel molecular targeting compound as K-samII/FGF-R2 phosphorylation inhibitor, Ki23057, for Scirrhous gastric cancer. Gastroenterology. 2006 Nov;131(5):1530-41. DOI:10.1053/j.gastro.2006.08.030 |
| | KI23057 Preparation Products And Raw materials |
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