8-iso-17-phenyl trinor Prostaglandin F2α

Request For Quotation
8-iso-17-phenyl trinor Prostaglandin F2α Suppliers list
Company Name: Shanghai Hongye Biotechnology Co. Ltd  
Tel: 400-9205774 400-920-5774
Email: sales@glpbio.cn
8-iso-17-phenyl trinor Prostaglandin F2α Basic information
Product Name:8-iso-17-phenyl trinor Prostaglandin F2α
Synonyms:8-iso-17-phenyl trinor Prostaglandin F2α
CAS:
MF:
MW:0
EINECS:
Product Categories:
Mol File:Mol File
8-iso-17-phenyl trinor Prostaglandin F2α Structure
8-iso-17-phenyl trinor Prostaglandin F2α Chemical Properties
solubility DMF: 50 mg/ml
DMSO: 50 mg/ml
Ethanol: 50 mg/mlPBS (pH 7.2): 1 mg/ml
Safety Information
MSDS Information
8-iso-17-phenyl trinor Prostaglandin F2α Usage And Synthesis
Description8-iso-17-phenyl trinor Prostaglandin F2α (8-iso-17-phenyl trinor PGF2α) is the C-8 epimer of bimatoprost (free acid), a metabolically stable analog of PGF2α. Bimatoprost (free acid) binds to the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2α.1 At the rat recombinant FP receptor expressed in CHO cells bimatoprost inhibits PGF2α binding with a Ki of 1.1 nM.2 There are no published studies of the pharmacological properties of 8-iso-17-phenyl trinor PGF2α.WARNING This product is not for human or veterinary use.
References[1] ANIL K. BALAPURE . Structural requirements for prostaglandin analog interaction with the ovine corpus luteum prostaglandin F2α receptor[J]. Biochemical pharmacology, 1989, 38 14: Pages 2375-2381. DOI: 10.1016/0006-2952(89)90478-4
[2] S. LAKE . Cloning of the rat and human prostaglandin F2α receptors and the expression of the rat prostaglandin F2α receptor[J]. FEBS Letters, 1994, 355 3: Pages 317-325. DOI: 10.1016/0014-5793(94)01198-2
8-iso-17-phenyl trinor Prostaglandin F2α Preparation Products And Raw materials
Tag:8-iso-17-phenyl trinor Prostaglandin F2α Related Product Information
BiMatoprost IMpurity III (15R)-BiMatoprost (5E)-BiMatoprost 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-, (5E)- 8-iso-17-phenyl trinor Prostaglandin F2β