| Company Name: |
Heterochem
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| Tel: |
027-88041443 13072715837 |
| Email: |
sales@hetero-chem.com |
| Products Intro: |
Product Name:Ethyl 3-aMino-1-phenyl-1H-pyrazole-4-carboxylate
CAS:16078-63-0
Purity:95%+ Package:1g;5g;10g;25g;50g
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| Company Name: |
Cool Pharm, Ltd
|
| Tel: |
021-60455363 18019463053 |
| Email: |
sales@coolpharm.com |
| Products Intro: |
Product Name:Ethyl3-amino-1-phenyl-1H-pyrazole-4-carboxylate
CAS:16078-63-0
Purity:98.0% Package:10g;25g;100g;500g;1kg;5kg;10kg
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| Company Name: |
Zhengzhou Guancheng Laboratory equipment Sales
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| Tel: |
0371-88888888 272369594 |
| Email: |
2723695949@qq.com |
| Products Intro: |
Product Name:1H-Pyrazole-4-carboxylic acid, 3-amino-1-phenyl-, ethyl ester
CAS:16078-63-0
Purity:97% Package:100g
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| | ethyl 3-aMino-1-phenyl-1H-pyrazole-4-carboxylate Basic information |
| Product Name: | ethyl 3-aMino-1-phenyl-1H-pyrazole-4-carboxylate | | Synonyms: | ethyl 3-aMino-1-phenyl-1H-pyrazole-4-carboxylate;3-Amino-1-phenyl-1H-pyrazole-4-carboxylic acid ethyl ester;1H-Pyrazole-4-carboxylic acid, 3-amino-1-phenyl-, ethyl ester;ethyl 3-amino-1-phenylpyrazole-4-carboxylate - [AC77927] | | CAS: | 16078-63-0 | | MF: | C12H13N3O2 | | MW: | 231.25 | | EINECS: | | | Product Categories: | | | Mol File: | 16078-63-0.mol |  |
| | ethyl 3-aMino-1-phenyl-1H-pyrazole-4-carboxylate Chemical Properties |
| Boiling point | 385.1±22.0 °C(Predicted) | | density | 1.25±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C(protect from light) | | pka | 1.26±0.10(Predicted) | | Appearance | White to off-white Solid |
| | ethyl 3-aMino-1-phenyl-1H-pyrazole-4-carboxylate Usage And Synthesis |
| Synthesis | Synthesis of 155-1. Sodium acetate trihydrate (1.40 g, 10.0 mmol) was added to a mixed acetic acid/water (10 mL/2 mL) solution of ethyl ethoxymethylcyanoacetate (869 mg, 5.1 mmol) and phenylhydrazine (500 mg, 4.6 mmol). The reaction mixture was placed in a microwave reactor and stirred at 130 °C for 30 min. After completion of the reaction, the mixture was cooled to room temperature and quenched by adding ice water. The resulting precipitate was collected by filtration and washed with a solvent mixture of ether and petroleum ether (1:1, v/v) to afford ethyl 3-amino-1-phenyl-1H-pyrazole-4-carboxylate (155-1) (1.03 g, 96% yield) as a yellow solid. | | References | [1] Patent: WO2017/7756, 2017, A1. Location in patent: Paragraph 207 |
| | ethyl 3-aMino-1-phenyl-1H-pyrazole-4-carboxylate Preparation Products And Raw materials |
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