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Lynnchem |
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86-(0)29-85992781 17792393971 |
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5-IsoxazolecarboxaMide, N-(2,3-dihydro-1,5- manufacturers
- ISPA-28
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- $680.00
-
2026-04-20
- CAS:1006335-39-2
- Purity:
- Supply Ability: 10g
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| | 5-IsoxazolecarboxaMide, N-(2,3-dihydro-1,5- Basic information |
| Product Name: | 5-IsoxazolecarboxaMide, N-(2,3-dihydro-1,5- | | Synonyms: | 5-IsoxazolecarboxaMide, N-(2,3-dihydro-1,5-;ISPA-28;N-(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-3-(1-ethyl-3-methyl-1H-pyrazol-4-yl)-4,5-dihydro-5-Isoxazolecarboxamide;ISPA-28 >=98% (HPLC);ISPA 28,ISPA28;5-Isoxazolecarboxamide, N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-3-(1-ethyl-3-methyl-1H-pyrazol-4-yl)-4,5-dihydro- | | CAS: | 1006335-39-2 | | MF: | C21H24N6O3 | | MW: | 408.45366 | | EINECS: | | | Product Categories: | | | Mol File: | 1006335-39-2.mol |  |
| | 5-IsoxazolecarboxaMide, N-(2,3-dihydro-1,5- Chemical Properties |
| density | 1.35±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | H2O: soluble5mg/mL, clear (warmed) | | form | powder | | pka | 10.98±0.20(Predicted) | | color | white to beige |
| | 5-IsoxazolecarboxaMide, N-(2,3-dihydro-1,5- Usage And Synthesis |
| Uses | ISPA-28 is a specific plasmodial surface anion channel (PSAC) antagonist. ISPA-28 binds directly and reversibly to CLAG3[1][2]. | | IC 50 | Plasmodium | | References | [1] Sanjay A Desai, et al. Ion and Nutrient Uptake by Malaria Parasite-Infected Erythrocytes. DOI:10.1111/j.1462-5822.2012.01790.x
[2] Wang Nguitragool, et al. Proteolysis at a Specific Extracellular Residue Implicates Integral Membrane CLAG3 in Malaria Parasite Nutrient Channels. |
| | 5-IsoxazolecarboxaMide, N-(2,3-dihydro-1,5- Preparation Products And Raw materials |
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