1-[(2R,3R,4S)-4-[Bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-hydroxy-2-furanyl]-2,4(1H,3H)-pyrimidinedione manufacturers
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| | 1-[(2R,3R,4S)-4-[Bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-hydroxy-2-furanyl]-2,4(1H,3H)-pyrimidinedione Basic information |
| Product Name: | 1-[(2R,3R,4S)-4-[Bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-hydroxy-2-furanyl]-2,4(1H,3H)-pyrimidinedione | | Synonyms: | 1-[(2R,3R,4S)-4-[Bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-hydroxy-2-furanyl]-2,4(1H,3H)-pyrimidinedione;1-(3’-O-[4,4’-dimethoxytrityl]-alpha-L-threofuranosyl)uridine;1-{3'-O-[(4",4"'-dimethoxytriphenyl)methyl]-α-L-threofuranosyl}uracil | | CAS: | 325683-90-7 | | MF: | C29H28N2O7 | | MW: | 516.54182 | | EINECS: | | | Product Categories: | | | Mol File: | 325683-90-7.mol | ![1-[(2R,3R,4S)-4-[Bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-hydroxy-2-furanyl]-2,4(1H,3H)-pyrimidinedione Structure](CAS/20150408/GIF/325683-90-7.gif) |
| | 1-[(2R,3R,4S)-4-[Bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-hydroxy-2-furanyl]-2,4(1H,3H)-pyrimidinedione Chemical Properties |
| density | 1.37±0.1 g/cm3 (20 ºC 760 Torr) |
| | 1-[(2R,3R,4S)-4-[Bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-hydroxy-2-furanyl]-2,4(1H,3H)-pyrimidinedione Usage And Synthesis |
| Uses | 1-(3’-O-[4,4’-dimethoxytrityl]-alpha-L-threofuranosyl)uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | | References | [1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
| | 1-[(2R,3R,4S)-4-[Bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-hydroxy-2-furanyl]-2,4(1H,3H)-pyrimidinedione Preparation Products And Raw materials |
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