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| | ((3R,4R)-4-aMinotetrahydro-2H-pyran-3-yl)carbaMate Basic information |
| Product Name: | ((3R,4R)-4-aMinotetrahydro-2H-pyran-3-yl)carbaMate | | Synonyms: | tert-butyl ((3R,4R)-4-aMinotetrahydro-2H-pyran-3-yl)carbaMate;((3R,4R)-4-aMinotetrahydro-2H-pyran-3-yl)carbaMate;Carbamic acid, N-[(3R,4R)-4-aminotetrahydro-2H-pyran-3-yl]-, 1,1-dimethylethyl ester;tert-butyl N-[(3R,4R)-4-aminotetrahydropyran-3-yl]carbamate;(3R,4R)-N3-Boc-tetrahydro-2H-pyran-3,4-diamine | | CAS: | 1240390-36-6 | | MF: | C10H20N2O3 | | MW: | 216.28 | | EINECS: | 604-604-1 | | Product Categories: | | | Mol File: | 1240390-36-6.mol |  |
| | ((3R,4R)-4-aMinotetrahydro-2H-pyran-3-yl)carbaMate Chemical Properties |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | Appearance | Colorless to light yellow Solid |
| | ((3R,4R)-4-aMinotetrahydro-2H-pyran-3-yl)carbaMate Usage And Synthesis |
| Synthesis | Step 8: Tert-butyl (3R,4R)-4-azidotetrahydro-2H-pyran-3-ylcarbamate (700 mg, 2.89 mmol) was dissolved in ethanol (10 mL) and palladium/carbon hydroxide catalyst was added. The reaction was carried out under hydrogen (1 atm) atmosphere for 6 hours. After completion of the reaction, the palladium/carbon hydroxide was removed by filtration and the filtrate was concentrated to afford tert-butyl (3R,4R)-4-aminotetrahydro-2H-pyran-3-ylcarbamate (610 mg). | | References | [1] Patent: WO2010/97248, 2010, A1. Location in patent: Page/Page column 38-39
[2] Patent: WO2013/78468, 2013, A1. Location in patent: Paragraph 0747; 0755
[3] Patent: US2017/15655, 2017, A1. Location in patent: Paragraph 1474-1475 |
| | ((3R,4R)-4-aMinotetrahydro-2H-pyran-3-yl)carbaMate Preparation Products And Raw materials |
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