| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:CGS 35601
CAS:849066-09-7
Package:25mg/RMB 10600;50mg/RMB 13800;100mg/RMB 17500
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L-Tryptophan, N-[[1-[[(2S)-2-Mercapto-4-Methyl-1-oxopentyl]aMino]cyclopentyl]carbonyl]- manufacturers
- CGS 35601
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- $1520.00 / 25mg
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2025-07-24
- CAS:849066-09-7
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | L-Tryptophan, N-[[1-[[(2S)-2-Mercapto-4-Methyl-1-oxopentyl]aMino]cyclopentyl]carbonyl]- Basic information |
| | L-Tryptophan, N-[[1-[[(2S)-2-Mercapto-4-Methyl-1-oxopentyl]aMino]cyclopentyl]carbonyl]- Chemical Properties |
| | L-Tryptophan, N-[[1-[[(2S)-2-Mercapto-4-Methyl-1-oxopentyl]aMino]cyclopentyl]carbonyl]- Usage And Synthesis |
| Uses | CGS 35601 is the inhibitor for endothelin-converting enzyme-1 (ECE-1), neutral endopeptidase 24.11 (NEP), and angiotensin-converting enzyme (ACE), with IC50s of 55, 2, and 22 nM, respectively. CGS 35601 suppresses the big endothelin-1 (big ET-1)- and angiotensin I-induced pressor response, and enhances circulation of atrial natriuretic peptide (ANP), regulates the cardiovascular function in SD rats[1]. | | References | [1] Trapani AJ, et al., CGS 35601 and its orally active prodrug CGS 37808 as triple inhibitors of endothelin-converting enzyme-1, neutral endopeptidase 24.11, and angiotensin-converting enzyme. J Cardiovasc Pharmacol. 2004 Nov;44 Suppl 1:S211-5. DOI:10.1097/01.fjc.0000166237.57077.d6 |
| | L-Tryptophan, N-[[1-[[(2S)-2-Mercapto-4-Methyl-1-oxopentyl]aMino]cyclopentyl]carbonyl]- Preparation Products And Raw materials |
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