PD-149163

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PD-149163 Basic information
Product Name:PD-149163
Synonyms:PD-149163;L-Leucine, N2-[(2S)-2,6-diaminohexyl]-L-lysyl-L-prolyl-L-tryptophyl-3-methyl-L-valyl-, ethyl ester
CAS:169528-11-4
MF:C42H71N9O6
MW:798.07
EINECS:
Product Categories:Agonists, Amino Acids & Derivatives, Heterocycles, Inhibitors, Pfizer Compounds, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:169528-11-4.mol
PD-149163 Structure
PD-149163 Chemical Properties
Boiling point 1034.5±65.0 °C(Predicted)
density 1.155±0.06 g/cm3(Predicted)
pka13.48±0.20(Predicted)
Safety Information
MSDS Information
PD-149163 Usage And Synthesis
UsesPD 149163 is a selective, brain penetrating Neurotensin NTR1 receptor agonist. Neurotensin agonists such as PD 149163 block the prepulse inhibition deficits produced by a 5-HT2A and an α1 agonist. As a result, PD 149163 shows pro-cognitive, antipsychotic and anxiolytic effects.
PD-149163 Preparation Products And Raw materials
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