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| | (2R,3R)-2-(2,4-difluorophenyl)-3-(tetrahydro-2H-pyran-2-yloxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Basic information |
| Product Name: | (2R,3R)-2-(2,4-difluorophenyl)-3-(tetrahydro-2H-pyran-2-yloxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol | | Synonyms: | Efinaconazole Impurity 39;(2R,3R)-2-(2,4-difluorophenyl)-3-(tetrahydro-2H-pyran-2-yloxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol;(2R,3R)-2-(2,4-difluorophenyl)-3-((tetrahydro-2H-pyran-2-yl)oxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol(WXG00770);(2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol 3-THP Ether;1H-1,2,4-Triazole-1-ethanol, α-(2,4-difluorophenyl)-α-[(1R)-1-[(tetrahydro-2H-pyran-2-yl)oxy]ethyl]-, (αR)-;Efinaconazole Impurity F;(2R,3R)-2-(2,4-Difluorophenyl)-3-((tetrahydro-2H-pyran-2-yl)...;(2R,3R)-2-(2,4-difluorophenyl)-3-tetrahydropyran-2-yloxy-1-(1,2,4-triazol-1-yl)butan-2-ol | | CAS: | 135133-23-2 | | MF: | C17H21F2N3O3 | | MW: | 353.36 | | EINECS: | | | Product Categories: | | | Mol File: | 135133-23-2.mol |  |
| | (2R,3R)-2-(2,4-difluorophenyl)-3-(tetrahydro-2H-pyran-2-yloxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Chemical Properties |
| Boiling point | 533.9±60.0 °C(Predicted) | | density | 1.35±0.1 g/cm3(Predicted) | | pka | 11.61±0.29(Predicted) |
| | (2R,3R)-2-(2,4-difluorophenyl)-3-(tetrahydro-2H-pyran-2-yloxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Usage And Synthesis |
| Uses | (2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol 3-THP Ether is an impurity of efinaconazole (E435070). |
| | (2R,3R)-2-(2,4-difluorophenyl)-3-(tetrahydro-2H-pyran-2-yloxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Preparation Products And Raw materials |
| Raw materials | 1-Propanone, 2-(acetyloxy)-1-(2,4-difluorophenyl)--->4-[(2R)-2-(3,4,5,6-tetrahydro-2H-pyran-2-yloxy)-propionyl]morpholine-->1-Propanone, 1-(2,4-difluorophenyl)-2-hydroxy-, (2R)--->2-((R)-1-((R)-2-(2,4-difluorophenyl)oxiran-2-yl)ethoxy)tetrahydro-2H-pyran-->2,4-difluoro phenyl magnesium bromide-->1,2,4-Triazole-->1,2,4-Triazolylsodium-->1-Bromo-2,4-difluorobenzene-->3,4-Dihydro-2H-pyran |
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