| Company Name: |
Pharmavoyager |
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15351203386 |
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2592141051@qq.com |
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| | 4-[4-[4-(trifluoroMethoxy)phenoxy]piperidin-1-yl]phenol Basic information |
| | 4-[4-[4-(trifluoroMethoxy)phenoxy]piperidin-1-yl]phenol Chemical Properties |
| Melting point | 113-114°C | | Boiling point | 461.2±45.0 °C(Predicted) | | density | 1.308±0.06 g/cm3(Predicted) | | storage temp. | Refrigerator, under inert atmosphere | | solubility | Chloroform (Slightly), Methanol (Slightly) | | pka | 12.25±0.30(Predicted) | | form | Solid | | color | Beige | | InChI | InChI=1S/C18H18F3NO3/c19-18(20,21)25-17-7-5-15(6-8-17)24-16-9-11-22(12-10-16)13-1-3-14(23)4-2-13/h1-8,16,23H,9-12H2 | | InChIKey | KXHMPYHAQBAPJK-UHFFFAOYSA-N | | SMILES | C1(O)=CC=C(N2CCC(OC3=CC=C(OC(F)(F)F)C=C3)CC2)C=C1 |
| | 4-[4-[4-(trifluoroMethoxy)phenoxy]piperidin-1-yl]phenol Usage And Synthesis |
| Uses | 4-[4-(4-Trifluoromethoxyphenoxy)piperidin-1-yl]phenol is an intermediate in the synthesis of Delamanid (D230660), a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in-vitro and in-vivo activity against drug-resistant strains of Mycobacterium tuberculosis. |
| | 4-[4-[4-(trifluoroMethoxy)phenoxy]piperidin-1-yl]phenol Preparation Products And Raw materials |
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