1-(2-Amino-6-(3,5-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl)-3-(tert-butyl)urea

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1-(2-Amino-6-(3,5-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl)-3-(tert-butyl)urea Basic information
Product Name:1-(2-Amino-6-(3,5-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl)-3-(tert-butyl)urea
Synonyms:1-(2-Amino-6-(3,5-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl)-3-(tert-butyl)urea;N-[2-Amino-6-(3,5-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea;EGF/FGF/PDGF receptor tyrosine kinase inhibitor;Urea, N-[2-amino-6-(3,5-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)-;PD 089828 Impurity 2;G85937
CAS:1135256-66-4
MF:C18H18Cl2N6O
MW:405.28
EINECS:
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Mol File:1135256-66-4.mol
1-(2-Amino-6-(3,5-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl)-3-(tert-butyl)urea Structure
1-(2-Amino-6-(3,5-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl)-3-(tert-butyl)urea Chemical Properties
density 1.416±0.06 g/cm3(Predicted)
pka10.02±0.43(Predicted)
Safety Information
MSDS Information
1-(2-Amino-6-(3,5-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl)-3-(tert-butyl)urea Usage And Synthesis
UsesN-[2-Amino-6-(3,5-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl]-N''-(1,1-dimethylethyl)urea is a broad tyrosine kinase inhibitor. N-[2-Amino-6-(3,5-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl]-N''-(1,1-dimethylethyl)urea inhibits PDGFr, FGFr, EGFr, and c-src tyrosine kinases.
1-(2-Amino-6-(3,5-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl)-3-(tert-butyl)urea Preparation Products And Raw materials
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