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ChemeGen |
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18818260767 |
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| | Nivalenol-13C15 solution Basic information |
| Product Name: | Nivalenol-13C15 solution | | Synonyms: | Nivalenol-13C15 solution;13C15-Nivalenol;13C15]-Nivalenol-25 μg/mL in ACN;Nivalenol-[13C15;Trichothec-9-en-8-one-13C15, 12,13-epoxy-3,4,7,15-tetrahydroxy-, (3α,4β,7α)-;Nivalenol 13C15 25 μg/mL in Acetonitrile | | CAS: | 911392-40-0 | | MF: | C15H20O7 | | MW: | 327.2 | | EINECS: | 804-499-3 | | Product Categories: | | | Mol File: | 911392-40-0.mol |  |
| | Nivalenol-13C15 solution Chemical Properties |
| density | 1.582±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | Fp | 2℃ | | storage temp. | -20°C | | solubility | Acetonitrile: Soluble |
| | Nivalenol-13C15 solution Usage And Synthesis |
| Uses | Nivalenol-13C15 is the 13C labeled Nivalenol (HY-N6801)[1]. Nivalenol, classified as type B trichotecenes toxins produced by Fusarium graminearum, is a fungal metabolite present in agricultural product[2]. Nivalenol induces cell death through caspase-dependent mechanisms and via the intrinsic apoptotic pathway. Nivalenol affects the immune system, causes emesis, growth retardation, reproductive disorders and has a haematotoxic/myelotoxic effect[3]. | | References | [1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-220. DOI:10.1177/1071100718790255
[2] Brya M, et al. Natural Occurrence of Nivalenol, Deoxynivalenol, and Deoxynivalenol-3-Glucoside in Polish Winter Wheat. Toxins (Basel). 2018 Feb 13;10(2). DOI:10.3390/toxins10020081
[3] Aupanun S, et al. Individual and combined mycotoxins deoxynivalenol, nivalenol, and fusarenon-X induced apoptosis in lymphoid tissues of mice after oral exposure. Toxicon. 2019 Jul;165:83-94. DOI:10.1016/j.toxicon.2019.04.017 |
| | Nivalenol-13C15 solution Preparation Products And Raw materials |
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