| Company Name: |
BOC Sciences |
| Tel: |
16314854226; +8616314854226 |
| Email: |
inquiry@bocsci.com |
GEODIN manufacturers
- (+)-Geodin
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- $683.00
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2026-07-27
- CAS:427-63-4
- Purity:
- Supply Ability: 10g
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| Product Name: | GEODIN | | Synonyms: | SPIRO[BENZOFURAN-2(3H),1'-[2,5]CYCLOHEXADIENE]-2'-CARBOXYLIC ACID, 5,7-DICHLORO-4-HYDROXY-6'-METHOXY-6-METHYL-3,4'-DIOXO-, METHYL ESTER;Estin, (+)-5,7-dichloro-4-hydroxy-6-methoxy-6-methyl-3,4-dioxo-spiro[benzofuran-2(3H),1-[2,5]cyclohexadiene]-2-carboxylic acid methyl ester;(1R)-3',4-Dioxo-4'-hydroxy-5',7'-dichloro-6-methoxy-6'-methylspiro[2,5-cyclohexadiene-1,2'(3'H)-benzofuran]-2-carboxylic acid methyl ester;(1R)-3',4-Dioxo-4'-hydroxy-5',7'-dichloro-6'-methyl-6-methoxyspiro[2,5-cyclohexadiene-1,2'(3'H)-benzofuran]-2-carboxylic acid methyl ester;(R)-5,7-Dichloro-4-hydroxy-6'-methoxy-6-methyl-3,4'-dioxospiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylic acid methyl ester;GEODIN;(+)-ESTIN;d-Geodin | | CAS: | 427-63-4 | | MF: | C17H12Cl2O7 | | MW: | 399.18 | | EINECS: | | | Product Categories: | | | Mol File: | 427-63-4.mol |  |
| | GEODIN Chemical Properties |
| Melting point | 235℃ | | alpha | D +140° (c = 0.8) | | Boiling point | 652.1±55.0 °C(Predicted) | | density | 1.61±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Chloroform: soluble; DMSO: soluble; Ethyl Acetate: soluble; Methanol: soluble | | form | A solid | | pka | 5.17±0.60(Predicted) | | color | Yellow |
| | GEODIN Usage And Synthesis |
| Description | (+)-Geodin is a fungal metabolite. It increases the fibrinolytic activity of bovine aortic endothelial cells (BAECs) when used at concentrations ranging from 50 to 150 μM. (+)-Geodin (1-100 μg/ml) also increases 2-deoxyglucose uptake by rat adipocytes. | | Uses | Geodin is an inhibitor of plasminogen activator inhibitor (PAI-1). | | storage | +4°C | | References | [1] C SHINOHARA. Enhancement of fibrinolytic activity of vascular endothelial cells by chaetoglobosin A, crinipellin B, geodin and triticone B.[J]. Journal of Antibiotics, 2000, 53 3: 262-268. DOI: 10.7164/antibiotics.53.262
[2] SEIICHI SATO. Identification and Preliminary SAR Studies of (+)-Geodin as a Glucose Uptake Stimulator for Rat Adipocytes[J]. Journal of Antibiotics, 2005, 58 9: 583-589. DOI: 10.1038/ja.2005.79 |
| | GEODIN Preparation Products And Raw materials |
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