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| | Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6 Basic information |
| | Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6 Chemical Properties |
| storage temp. | -20°C | | form | liquid | | biological source | rabbit |
| WGK Germany | nwg | | Storage Class | 10 - Combustible liquids |
| | Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6 Usage And Synthesis |
| Uses | Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed. | | Biological Activity | Protein arginine N-methyltransferases, such as PRMT6, catalyze the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine.Protein arginine N-methyltransferases, such as PRMT6, catalyze the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine.[supplied by OMIM]. |
| | Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6 Preparation Products And Raw materials |
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