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| | Anti-Tryptophan Hydroxylase 2 Basic information |
| Product Name: | Anti-Tryptophan Hydroxylase 2 | | Synonyms: | Anti-TPH2 antibody produced in rabbit;Anti-TPH2 antibody produced in goat;Anti-FLJ37295;Anti-NTPH;Anti-Tryptophan Hydroxylase 2;tph2;tphR;wu:fq15a04 | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![Anti-Tryptophan Hydroxylase 2 Structure]() |
| | Anti-Tryptophan Hydroxylase 2 Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution | | biological source | rabbit |
| Hazard Codes | Xn | | Risk Statements | 22 | | WGK Germany | WGK 2 | | Storage Class | 10 - Combustible liquids |
| | Anti-Tryptophan Hydroxylase 2 Usage And Synthesis |
| Uses | Suggested starting dilutions are as follows: IHC-P: 1:100-1:1000, WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. | | Biological Activity | Tryptophan hydroxylase (TPH; EC 1.14.16.4) is the rate-limiting enzyme in the synthesis of serotonin (5-hydroxytryptamine, or 5HT). 5HT is causally involved in numerous central nervous activities, and it has several functions in peripheral tissues, including the maintenance of vascular tone and gut motility. This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. The human genome contains two related tryptophan hydroxylases, one on chromosome 11p15-p14 and one on chromosome 12q21. This gene is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by the mouse ortholog. Publication Note: This RefSeq record includes a subset of the publications th at are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1805 AY098914.1 1-1805 1806-2360 AC090109.15 122981-123535 |
| | Anti-Tryptophan Hydroxylase 2 Preparation Products And Raw materials |
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