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| | Vascular Endothelial Growth Inhibitor Basic information |
| Product Name: | Vascular Endothelial Growth Inhibitor | | Synonyms: | VEGI isoform;VEGI/TNFSF-15 human;VEGI192A;TNFSF15;Vascular Endothelial Growth Inhibitor;TL-1A human;VEGI;Recombinant Mouse TL1A/Tnfsf15 Protein, No Tag | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![Vascular Endothelial Growth Inhibitor Structure]() |
| | Vascular Endothelial Growth Inhibitor Chemical Properties |
| storage temp. | -20°C | | form | lyophilized | | biological source | human |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | Vascular Endothelial Growth Inhibitor Usage And Synthesis |
| Uses | TL-1A belongs to the TNF superfamily of ligands. It is expressed predominantly in endothelial cells, and to a lesser extent in placenta, lung, kidney, skeletal muscle, pancreas, small intestine and colon. TL-1A inhibits endothelial cell proliferation and angiogenesis, and has been shown to induce NFkB activation, caspase activity, and apoptosis in responding cell lines. TL-1A interacts with TNFRSF25/DR3 receptor, but can also bind to a decoy receptor TNFRSF21/DR6. Recombinant human TL-1A is a 22.0 kDa polypeptide of 194 amino acid residues. | | Biological Activity | TL-1A belongs to the TNF superfamily of ligands. Recombinant human TL-1A is a 22.0 kDa polypeptide of 194 amino acid residues. |
| | Vascular Endothelial Growth Inhibitor Preparation Products And Raw materials |
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