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16314854226 |
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info@bocsci.com |
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InvivoChem |
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TCS HDAC6 20b manufacturers
- TCS HDAC6 20b
-
- $1090.00
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2026-07-03
- CAS:956154-63-5
- Purity: 99.48%
- Supply Ability: 10g
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| | TCS HDAC6 20b Basic information |
| Product Name: | TCS HDAC6 20b | | Synonyms: | TCS HDAC6 20b;DQZMLPMCOMRJOR-MOVGKWKRSA-N;S-[(6S)-7-(1-adamantylamino)-6-[(2-methylpropan-2-yl)oxycarbonylamino]-7-oxoheptyl] 2-methylpropanethioate;2-Methylpropanethioic acid-S-[(6S)-6-[[(1,1-dimethylethoxy)carbonyl]amino]-7-oxo-7-(tricyclo[3.3.1.13,7]dec-1-ylamino)heptyl] ester;Propanethioic acid, 2-methyl-, S-[(6S)-6-[[(1,1-dimethylethoxy)carbonyl]amino]-7-oxo-7-(tricyclo[3.3.1.13,7]dec-1-ylamino)heptyl] ester | | CAS: | 956154-63-5 | | MF: | C26H44N2O4S | | MW: | 480.7 | | EINECS: | | | Product Categories: | | | Mol File: | 956154-63-5.mol |  |
| | TCS HDAC6 20b Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | White Oily foam |
| | TCS HDAC6 20b Usage And Synthesis |
| Description | TCS HDAC6 20b is an inhibitor of histone deacetylase 6 (HDAC6) that inhibits the growth of HCT116 cells synergistically when used at a concentration of 5 μM in combination with paclitaxel , but it has no activity on cell growth in HCT116 cells when used alone. It inhibits cell growth of α-positive MCF-7 breast cancer cells treated with estrogen but not untreated cells. | | Uses | TCS HDAC6 20b is a histone deacetylase 6 (HDAC6)-selective inhibitor. | | references | [1]. suzuki t, kouketsu a, itoh y, et al. highly potent and selective histone deacetylase 6 inhibitors designed based on a small-molecular substrate. j med chem, 2006, 49(16): 4809-4812. [2]. itoh y, suzuki t, kouketsu a, et al. design, synthesis, structure--selectivity relationship, and effect on human cancer cells of a novel series of histone deacetylase 6-selective inhibitors. j med chem, 2007, 50(22): 5425-5438. |
| | TCS HDAC6 20b Preparation Products And Raw materials |
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