- Axitinib sulfoxide
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- $765.00 / 5mg
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2025-04-27
- CAS:1347304-18-0
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | Axitinib Impurity a Basic information |
| Product Name: | Axitinib Impurity a | | Synonyms: | Axitinib Impurity a;Axitinib Sulfoxide;N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfinyl]benzamide;N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfinyl]benzamide;Axitinib Impurity 5/Axitinib Sulfoxide/N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfinyl]-benzamide;Benzamide, N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfinyl]-;Axitinib C;Axitinib sulfoxide (AG028458 | | CAS: | 1347304-18-0 | | MF: | C22H18N4O2S | | MW: | 402.47 | | EINECS: | | | Product Categories: | | | Mol File: | 1347304-18-0.mol |  |
| | Axitinib Impurity a Chemical Properties |
| Melting point | >225 (dec.) | | Boiling point | 720.6±60.0 °C(Predicted) | | density | 1.43±0.1 g/cm3(Predicted) | | storage temp. | Refrigerator | | solubility | DMSO (Slightly), Methanol (Slightly, Heated) | | pka | 11.70±0.40(Predicted) | | form | Solid | | color | Light Yellow |
| | Axitinib Impurity a Usage And Synthesis |
| Description | Axitinib sulfoxide is a major inactive metabolite of the tyrosine kinase inhibitor axitinib . It is formed from axitinib primarily by the cytochrome P450 (CYP) isoform CYP3A4 with minor contributions from CYP3A5 and CYP2C19. | | Uses | Axitinib Sulfoxide is a major metabolite of Axitinib (A794650), a tyrosine kinase inhibitor. Axitinib is used in cancer therapy. |
| | Axitinib Impurity a Preparation Products And Raw materials |
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