| Company Name: |
BePharm Ltd |
| Tel: |
400-685-9117 |
| Email: |
market@bepharm.com |
|
| | 4,5-Dibromo-3-methylthiophene-2-carboxylic acid Basic information |
| | 4,5-Dibromo-3-methylthiophene-2-carboxylic acid Chemical Properties |
| Melting point | 225-226 °C | | Boiling point | 369.8±42.0 °C(Predicted) | | density | 2.141±0.06 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | pka | 3.48±0.10(Predicted) | | Appearance | White to off-white Solid |
| | 4,5-Dibromo-3-methylthiophene-2-carboxylic acid Usage And Synthesis |
| Preparation | 4,5-Dibromo-3-methyl-2-thiophenecarboxylic acid synthesis: 4,5-dibromo-3-methyl-2-thiophenecarbonitrile (26.2 g, 92.2 mmol), EtOH (175 mL), water (175 mL), and NaOH (18.6 g, 466 mmol) were stirred together at 80°C for 1 h. The solvent was removed, the solids were collected by filtration, dissolved in water, and washed with CH2Cl2. The water layer was acidified with 37% HCl, the white solid was collected by filtration and dried under vacuum at 60°C to give 25.9 g (94% wt.) of 4,5-dibromo-3-methyl-2-thiophenecarboxylic acid: m.p. 225-226°C; 1H NMR (CDCl3) 2.5 (s). |
| | 4,5-Dibromo-3-methylthiophene-2-carboxylic acid Preparation Products And Raw materials |
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