N2-(Isopropylphenoxyacetyl)-2'-O-propargylguanosine

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N2-(Isopropylphenoxyacetyl)-2'-O-propargylguanosine manufacturers
N2-(Isopropylphenoxyacetyl)-2'-O-propargylguanosine Basic information
Product Name:N2-(Isopropylphenoxyacetyl)-2'-O-propargylguanosine
Synonyms:N2-(Isopropylphenoxyacetyl)-2'-O-propargylguanosine;N2-(Isopropylphenoxyacetyl)-2’-O-propargylguanosine
CAS:2095417-23-3
MF:C24H27N5O7
MW:497.50048
EINECS:
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Mol File:2095417-23-3.mol
N2-(Isopropylphenoxyacetyl)-2'-O-propargylguanosine Structure
N2-(Isopropylphenoxyacetyl)-2'-O-propargylguanosine Chemical Properties
density 1.46±0.1 g/cm3(Predicted)
pka7.19±0.20(Predicted)
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MSDS Information
N2-(Isopropylphenoxyacetyl)-2'-O-propargylguanosine Usage And Synthesis
UsesN2-(Isopropylphenoxyacetyl)-2’-O-propargylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. N2-(Isopropylphenoxyacetyl)-2’-O-propargylguanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
References[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
N2-(Isopropylphenoxyacetyl)-2'-O-propargylguanosine Preparation Products And Raw materials
Tag:N2-(Isopropylphenoxyacetyl)-2'-O-propargylguanosine(2095417-23-3) Related Product Information
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