JWH 019 N-(6-hydroxyhexyl) β-D-Glucuronide

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JWH 019 N-(6-hydroxyhexyl) β-D-Glucuronide Suppliers list
Company Name: Shanghai Hongye Biotechnology Co. Ltd  
Tel: 400-9205774 400-920-5774
Email: sales@glpbio.cn
JWH 019 N-(6-hydroxyhexyl) β-D-Glucuronide Basic information
Product Name:JWH 019 N-(6-hydroxyhexyl) β-D-Glucuronide
Synonyms:JWH 019 N-(6-hydroxyhexyl) β-D-Glucuronide;AWPUOPYMUOPGIN-SQQOACJHSA-N;JWH 019 N-(6-hydroxyhexyl) .beta.-D-Glucuronide;β-D-Glucopyranosiduronic acid, 6-[3-(1-naphthalenylcarbonyl)-1H-indol-1-yl]hexyl;(2S,3S,4S,5R,6R)-6-((6-(3-(1-naphthoyl)-1H-indol-1-yl)hexyl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylicacid
CAS:1630023-00-5
MF:C31H33NO8
MW:547.596
EINECS:
Product Categories:
Mol File:1630023-00-5.mol
JWH 019 N-(6-hydroxyhexyl) β-D-Glucuronide Structure
JWH 019 N-(6-hydroxyhexyl) β-D-Glucuronide Chemical Properties
Boiling point 818.2±65.0 °C(Predicted)
density 1.38±0.1 g/cm3(Predicted)
solubility DMSO: 10 mg/ml
form A crystalline solid
pka2.83±0.70(Predicted)
Safety Information
MSDS Information
JWH 019 N-(6-hydroxyhexyl) β-D-Glucuronide Usage And Synthesis
DescriptionJWH 019 is a cannabimimetic indole that shows a high-affinity for both the central cannabinoid (CB1) (Ki = 9.8 nM) and the peripheral cannabinoid (CB2) (Ki = 5.6 nM) receptors.1 JWH 019 N-(6-hydroxyhexyl) β-D-Glucuronide is an expected major urinary metabolite of JWH 019, based on the metabolism of similar cannabimimetics.2,3,4 The physiological and toxicological properties of this compound have not been tested. This product is intended for forensic and research applications.
References1. Aung, M.M., Griffin, G., Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding Drug Alcohol Depend. 60(2),133-140(2000).
2. Sobolevsky, T., Prasolov, I., and Rodchenkov, G. Detection of JWH-018 metabolites in smoking mixture post-administration urine Forensic Sci. Int. 200(1-3),141-147(2010).
3. Wintermeyer, A., Mller, I., Thevis, M., et al. In vitro phase I metabolism of the synthetic cannabimimetic JWH-018 Anal. Bioanal. Chem. 398(5),2141-2153(2010).
4. Chimalakonda, K.C., Moran, C.L., Kennedy, P.D., et al. Solid-phase extraction and quantitative measurement of omega and omega-1 metabolites of JWH-018 and JWH-073 in human urine Anal. Chem. 83(16),6381-6388(2011).
JWH 019 N-(6-hydroxyhexyl) β-D-Glucuronide Preparation Products And Raw materials
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