- 1,2-DIBROMO-4-FLUOROBENZENE
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- $101.00 / 1KG
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2023-12-29
- CAS:2369-37-1
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
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| | 1,2-Dibromo-4-fluorobenzene Basic information |
| Product Name: | 1,2-Dibromo-4-fluorobenzene | | Synonyms: | 3,4-DIBROMOFLUOROBENZENE;1,2-Dibromo-4-fluorobenzene,98%;1,2-Dibromo-4-fluorobenzene 99%;1,2-Dibromo-4-fluorobenzene99%;1,2-DIBROMO-4-FLUOROBENZENE;1,2-DibroMo-4-fluorobenzene[3,4-DibroMofluorobenzene];1,2-Dibromo-4-fluorobezene;3,4-Dibromo-1-fluorobenzene | | CAS: | 2369-37-1 | | MF: | C6H3Br2F | | MW: | 253.89 | | EINECS: | 219-131-1 | | Product Categories: | Bromine Compounds;Fluorine Compounds;Fluorine series | | Mol File: | 2369-37-1.mol |  |
| | 1,2-Dibromo-4-fluorobenzene Chemical Properties |
| Melting point | 69℃ | | Boiling point | 220℃ | | density | 2.014 | | refractive index | 1.5780-1.5820 | | Fp | 87℃ | | form | clear liquid | | color | Colorless to Light yellow | | CAS DataBase Reference | 2369-37-1(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36/37/39 | | Hazard Note | Irritant | | HS Code | 2903998090 |
| Provider | Language |
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ALFA
| English |
| | 1,2-Dibromo-4-fluorobenzene Usage And Synthesis |
| Reactivity Profile |
The Suzuki–Miyaura reaction of 1,2- dibromo-4-fluorobenzene with two equivalents of arylboronic acids 2a–d, i,v afforded the fluorinated terphenyls 15a–f in moderate to good yields. The best yields were obtained using 2.2 equivalents of the aryl boronic acid, Pd(PPh3)4 (0.03 equiv) as the catalyst, and Cs2CO3 (2.2 equiv) as the base (1,4-dioxane, 90 8C, 8 h). The low site-selectivity in the case of 1,2-dibromo-4-fluorobenzene (13) can be explained by the fact that the positions 1 and 2, located meta and para to the fluorine atom, are sterically and electronically very similar[1].
| | References | [1] Muhammad Sharif . “Synthesis of functionalized fluorinated terphenyls by site-selective Suzuki–Miyaura cross-coupling reactions of dibrominated fluorobenzenes.” Journal of Fluorine Chemistry 146 (2013): Pages 19-36.
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| | 1,2-Dibromo-4-fluorobenzene Preparation Products And Raw materials |
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