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| | Ethanedioic acid,1-methyl ester, potassium salt (1:1) Basic information |
| Product Name: | Ethanedioic acid,1-methyl ester, potassium salt (1:1) | | Synonyms: | Potassium 2-methoxy-2-oxoacetate;Tiotropium Bromide Impurity 8 Potassium Salt;potassium oxalate monomethyl ester;Ethanedioic acid,1-methyl ester, potassium salt;Methyl potassium oxalate 95%;Ethanedioic acid, monomethyl ester, potassium salt;Ethanedioicacid,monomethylester,potassiumsalt(1:1);Potassium methoxy(oxo)acetate | | CAS: | 10304-09-3 | | MF: | C3H3KO4 | | MW: | 142.15182 | | EINECS: | | | Product Categories: | | | Mol File: | 10304-09-3.mol |  |
| | Ethanedioic acid,1-methyl ester, potassium salt (1:1) Chemical Properties |
| Melting point | 197 °C | | storage temp. | Inert atmosphere,Room Temperature | | form | solid | | color | White |
| | Ethanedioic acid,1-methyl ester, potassium salt (1:1) Usage And Synthesis |
| Synthesis | General procedure for the synthesis of potassium 2-methoxy-2-oxoacetate from dimethyl oxalate: 1.2 g of dimethyl oxalate and 0.98 g of potassium acetate were dissolved in a mixed solvent of 10 mL of methanol and 10 mL of water. The reaction mixture was stirred at 80 °C for 3 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure. A white solid product was obtained in quantitative yield. | | References | [1] Patent: WO2005/53609, 2005, A2. Location in patent: Page/Page column 25-26
[2] Patent: CN105439883, 2016, A. Location in patent: Paragraph 0051
[3] Chemical and Pharmaceutical Bulletin, 1998, vol. 46, # 3, p. 514 - 517
[4] Journal of the American Chemical Society, |
| | Ethanedioic acid,1-methyl ester, potassium salt (1:1) Preparation Products And Raw materials |
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