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Product Name:7-Dehydrocholesterol-25,26,26,26,27,27,27-d7
CAS:388622-58-0
Purity:>=99 atom % D, >=98% (CP) Package:5MG Remarks:774898-5MG
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Shanghai EFE Biological Technology Co., Ltd.
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Product Name:(3β)-7-Dehydro Cholesterol-d7 (Major)
CAS:388622-58-0
Purity:95% Package:0.5mg;1mg
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Nanjing Haolv Biotechnology Co.,Ltd
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Product Name:7-Dehydrocholesterol-25,26,26,26,27,27,27-d7
CAS:388622-58-0
Purity:98% Package:5g;25g;100g Remarks:Steroids
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Shanghai Hongye Biotechnology Co. Ltd
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Product Name:7-dehydro Cholesterol-d7
CAS:388622-58-0
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| | 7-Dehydrocholesterol-25,26,26,26,27,27,27-d7 Basic information |
| Product Name: | 7-Dehydrocholesterol-25,26,26,26,27,27,27-d7 | | Synonyms: | (32)-7-Dehydro Cholesterol-d7 (Major);7-dehydro Cholesterol-d7;7-Dehydrocholesterol-25,26,26,26,27,27,27-d7;Cholesta-5,7-dien-25,26,26,26,27,27,27-d7-3-ol, (3b)-;(3β)-7-Dehydro Cholesterol-d7 (Major);(3β)-7-Dehydro Cholesterol-d7
(See also D229462);2H7]-7-Dehydrocholesterol;Cholecalciferol EP Impurity B-d7 (3-beta-7-Dehydro Cholesterol-d7) | | CAS: | 388622-58-0 | | MF: | C27H44O | | MW: | 384.65 | | EINECS: | | | Product Categories: | | | Mol File: | 388622-58-0.mol |  |
| | 7-Dehydrocholesterol-25,26,26,26,27,27,27-d7 Chemical Properties |
| storage temp. | -70°C | | solubility | Soluble in methanol(warmed), slightly soluble in chloroform | | form | solid | | Stability: | Light Sensitive | | InChIKey | UCTLRSWJYQTBFZ-PDTMYDHWNA-N | | SMILES | C[C@]12CC[C@]3([H])[C@]4(CC[C@H](O)CC4=CC=C3[C@]1([H])CC[C@]2([H])[C@H](C)CCCC([H])(C([H])([H])[H])C([H])([H])[H])C |&1:1,4,6,9,16,20,22,r| | | CAS Number Unlabeled | 434-16-2 |
| WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | 7-Dehydrocholesterol-25,26,26,26,27,27,27-d7 Usage And Synthesis |
| Uses | 7-dehydrocholesterol-d7 has been used:
- as an internal standard: to spike Chlamydomonas CC-125 lipid extract for mass spectroscopy analysis
- in liquid chromatography–mass spectrometry (LC-MS) for cultured cells oxysterol analysis
- to treat and label SRD-1 cell (chinese hamster ovary (CHO) mutant cell-line) for gas chromatography/mass spectrometry (GC/MS) analysis
| | General Description | 7-dehydrocholesterol (7-DHC) is a cholesterol precursor and is localized in basal epidermal keratinocytes. 7DHC on photolysis in the presence of ultraviolet light B generates previtamin D3. The enzyme 7-dehydrocholesterol reductase (DHCR7) catalyzes the reduction of C(7-8) double bond of 7-DHC to cholesterol. 7-dehydrocholesterol-d7 is a deuterated derivative of 7-dehydrocholesterol. | | Biochem/physiol Actions | 7-Dehydrocholesterol (7-DHC) is used as a precursor for microbial vitamin D3 production. Impairment of 7-dehydrocholesterol reductase (DHCR7) functionality leads to 7-DHC accumulation and is implicated in Smith-Lemli-Opitz syndrome (SLOS). |
| | 7-Dehydrocholesterol-25,26,26,26,27,27,27-d7 Preparation Products And Raw materials |
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