2,6-Bis(1,1-dimethylethyl)-4-[[(4-methoxyphenyl)dimethylsilyl]methoxy]phenol
| 中文名称 | 2,6-Bis(1,1-dimethylethyl)-4-[[(4-methoxyphenyl)dimethylsilyl]methoxy]phenol |
|---|---|
| 中文同义词 | 化合物 T10063;化合物LDL-IN-3;化合物LDL-IN-3,10 MM DMSO 溶液 |
| 英文名称 | 2,6-Bis(1,1-dimethylethyl)-4-[[(4-methoxyphenyl)dimethylsilyl]methoxy]phenol |
| 英文同义词 | 2,6-Bis(1,1-dimethylethyl)-4-[[(4-methoxyphenyl)dimethylsilyl]methoxy]phenol;LDL-IN-3;Phenol, 2,6-bis(1,1-dimethylethyl)-4-[[(4-methoxyphenyl)dimethylsilyl]methoxy]-;LDLIN3,LDL IN 3;LDL-IN-3, 10 mM in DMSO |
| CAS号 | 180908-67-2 |
| 分子式 | C24H36O3Si |
| 分子量 | 400.63 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 180908-67-2.mol |
| 结构式 | ![2,6-Bis(1,1-dimethylethyl)-4-[[(4-methoxyphenyl)dimethylsilyl]methoxy]phenol 结构式](CAS/20180527/GIF/180908-67-2.gif) |
2,6-Bis(1,1-dimethylethyl)-4-[[(4-methoxyphenyl)dimethylsilyl]methoxy]phenol 性质
| 沸点 | 476.0±45.0 °C(Predicted) |
|---|---|
| 密度 | 1.02±0.1 g/cm3(Predicted) |
| 储存条件 | Store at -20°C |
| 溶解度 | 溶于二甲基亚砜 |
| 酸度系数(pKa) | 13.11±0.40(Predicted) |
LDL-IN-3是从专利WO/2005/039596A1，化合物实例C25和专利US 6133467，化合物实例3中提取的抗动脉粥样硬化化合物。
LDL-IN-3 is antioxidant which inhibits low density lipoprotein (LDL) lipid peroxidation and is useful as anti-atherosclerotic agents.
LDL-IN-3 decreases serum cholesterol, TBARS and the amount of aortic lesions (57 %) in comparison with control rabbits. LDL-IN-3 is found in very high concentrations in the serum (182.4 μg/mL) and livers (323 μg/mL).