| Company Name: |
MedChemexpress LLC
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021-58955995 |
| Email: |
sales@medchemexpress.cn |
| Products Intro: |
Product Name:3,4-Dihydro-2-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-1(2H)-naphthalenone
CAS:149247-12-1
Purity:780RMB/1mg Package:>98%
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| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:QF0301B
CAS:149247-12-1
Remarks:QF0301B is an α1 adrenergic receptor antagonist and shows noncompetitive low action in 5-HT3, muscarinic and nicotinic receptors, or as Ca2+ antagonist.
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3,4-Dihydro-2-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-1(2H)-naphthalenone manufacturers
- QF0301B
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- $700.00
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2026-05-11
- CAS:149247-12-1
- Purity: 100.00%
- Supply Ability: 10g
- QF0301B
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- $1800.00
-
2025-06-18
- CAS:149247-12-1
- Purity: 99.16%
- Supply Ability: 10g
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| | 3,4-Dihydro-2-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-1(2H)-naphthalenone Basic information |
| | 3,4-Dihydro-2-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-1(2H)-naphthalenone Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble in DMSO |
| | 3,4-Dihydro-2-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-1(2H)-naphthalenone Usage And Synthesis |
| Uses | QF0301B is an α1 adrenergic receptor antagonist and a low α2 adrenoceptor, 5-HT2A, and histamine H1 receptor blocker. | | in vivo | QF0301B (0.1-0.2 mg/kg iv) can cause a pronounced and prolonged fall in mean arterial blood pressure accompanied by bradycardia. QF0301B does not significantly modify the cardiovascular effects of either 5-hydroxytryptamine (serotonin, 5-HT, 75 mg/kg iv) or the selective a2-adrenoceptor agonist B-HT 920 (0.2 mg/kg iv), but markedly inhibits the hypertensive effect of noradrenaline (5 mg/kg iv), a nonselective a-adrenergic receptor agonist[1]. | | References | [1] Orallo F, et al. In vivo and in vitro pharmacological studies of a new hypotensive compound (QF0301B) in rat: Comparison with prazosin, a known α1-adrenoceptor antagonist. Vascul Pharmacol. 2003 Feb;40(2):97-108. |
| | 3,4-Dihydro-2-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-1(2H)-naphthalenone Preparation Products And Raw materials |
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