Biotin-PEG4- Picolyl Azide

Biotin-PEG4- Picolyl Azide Suppliers list

Company Name:	BOC Sciences
Tel:	+1-631-485-4226
Email:	inquiry@bocsci.com
Products Intro:	Product Name:Biotin-PEG4-Picolyl azide CAS:2222687-71-8 Purity:>=95% Package:25 mg Remarks:Reach out to us for more information about custom solutions.

Company Name:	TargetMol Chemicals Inc.
Tel:	+1-781-999-5354; +17819995354
Email:	marketing@targetmol.com
Products Intro:	Product Name:Biotin-PEG4-Picolyl azide CAS:2222687-71-8 Purity:98.00% Package:1mg;108USD\|5mg;272USD\|10mg;438USD Remarks:REAGENT;FOR LABORATORY USE ONLY

Company Name:	Alfa Chemistry
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Products Intro:	Product Name:Biotin-PEG4-picolyl azide CAS:2222687-71-8 Purity:98%+

Company Name:	Hangzhou MolCore BioPharmatech Co.,Ltd.
Tel:	+86-057181025280; +8617767106207
Email:	sales@molcore.com
Products Intro:	Product Name:Biotin-PEG4-Picolyl azide CAS:2222687-71-8 Purity:NLT 98% Remarks:MC457375

Company Name:	Jilin Chinese Academy of Sciences-yanshen Technology
Tel:	+undefined18143011203
Email:	info@chemextension.com
Products Intro:	Product Name:Biotin-PEG4-Picolyl-azide CAS:2222687-71-8 Purity:95%+ Package:1g;5g;10g;25g;50g;100g; Remarks:accept Custom Synthesis Services, support large packing

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Biotin-PEG4- Picolyl Azide Basic information

Biotin-PEG4- Picolyl Azide Chemical Properties

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Biotin-PEG4- Picolyl Azide Usage And Synthesis

Description	Biotin-PEG4-Picolyl azide is a biotin reagent which can be conjugated with alkyne-containing biomolecules. This biotin reagent incorporates a copper-chelating motif that dramatically accelerates the Cu(I)-catalyzed Click Chemistry. The use of Biotin Picolyl Azide instead of conventional Biotin Azide allows for at least a tenfold reduction in the concentration of the copper catalyst without sacrificing the efficiency of labeling. The hydrophilic spacer arm provides better solubility to the labeled molecules in aqueous media.
Uses	Biotin-PEG4-Picolyl azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Biotin-PEG4-Picolyl azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50	PEGs
References	[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Biotin-PEG4- Picolyl Azide Preparation Products And Raw materials

Tag:Biotin-PEG4- Picolyl Azide(2222687-71-8) Related Product Information

Biotin-PEG4-Amide-C6-Azide 15-[D(+)-BIOTINYLAMINO]-4,7,10,13-TETRAOXAPENTADECANOIC ACID Biotin-PEG2-C6-Azide UV Cleavable Biotin-PEG2-Azide Biotin-PEG4-Methyltetrazine Acetylene-PEG4-biotin conjugate Biotin-PEG2-azide Biotin-PEG4-N3 Biotin-PEG₄-Azide Biotin-PEG2-C4-Alkyne DBCO-PEG4-biotin 1H-Thieno[3,4-d]iMidazole-4-pentanaMide, hexahydro-2-oxo-N-2-propynyl-, (3aS,4S,6aR)- (3aS,4S,6aR)-Hexahydro-2-oxo-N-(15-oxo-3,6,9,12-tetraoxa-16-azanonadec-18-yn-1-yl)-1H-thieno[3,4-d]imidazole-4-pentanamide Azide-SS-biotin (4E)-TCO-PEG4-biotin EZ-LINK (TM) PFP-BIOTIN, 50 MG Biotin-PEG4-PFP ester 1H-Thieno[3,4-d]imidazole-4-pentanamide,N-(14-amino-3,6,9,12-tetraoxatetradec-1-yl)hexahydro-2-oxo-,(3aS,4S,6aR)-

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