Tri(Amino-PEG5-amide)-amine TFA salt

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Tri(Amino-PEG5-amide)-amine TFA salt Basic information
Product Name:Tri(Amino-PEG5-amide)-amine TFA salt
Synonyms:Tri(Amino-PEG5-amide)-amine TFA salt;CUN 13528;4,7,10,13,16-Pentaoxaoctadecanamide, N,N',N''-(nitrilotri-2,1-ethanediyl)tris[18-amino-
CAS:2055013-52-8
MF:C45H93N7O18
MW:1020.26
EINECS:
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Mol File:2055013-52-8.mol
Tri(Amino-PEG5-amide)-amine TFA salt Structure
Tri(Amino-PEG5-amide)-amine TFA salt Chemical Properties
Boiling point 1025.2±65.0 °C(Predicted)
density 1.130±0.06 g/cm3(Predicted)
solubility Soluble in Water, DMSO, DMF
pka15.11±0.46(Predicted)
Safety Information
MSDS Information
Tri(Amino-PEG5-amide)-amine TFA salt Usage And Synthesis
DescriptionTri(Amino-PEG5-amide)-amine is a water soluble PEG linker. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
UsesTri(Amino-PEG5-amide)-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50PEGs
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Tri(Amino-PEG5-amide)-amine TFA salt Preparation Products And Raw materials
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