4-(4-Fluorobenzoyl)-1-(4-phenylbutyl)piperidine oxalate manufacturers
- 4F 4PP oxalate
-
- $51.00
-
2026-07-15
- CAS:144734-36-1
- Purity: 98.59%
- Supply Ability: 10g
|
| | 4-(4-Fluorobenzoyl)-1-(4-phenylbutyl)piperidine oxalate Basic information |
| Product Name: | 4-(4-Fluorobenzoyl)-1-(4-phenylbutyl)piperidine oxalate | | Synonyms: | 4F 4PP OXALATE;(4-Fluorophenyl)(1-(4-phenylbutyl)piperidin-4-yl)methanone oxalate;selective,potentials,Inhibitor,Serotonin Receptor,4F 4PP,ketanserin,5-HT Receptor,inhibit,4F 4PP oxalate,5-HT2C,5-hydroxytryptamine Receptor,DAMGO;4F 4PP oxalate, 10 mM in DMSO;4-(4-Fluorobenzoyl)-1-(4-phenylbutyl)piperidine oxalate | | CAS: | 144734-36-1 | | MF: | C24H28FNO5 | | MW: | 429.48 | | EINECS: | | | Product Categories: | Serotonin receptor | | Mol File: | Mol File |  |
| | 4-(4-Fluorobenzoyl)-1-(4-phenylbutyl)piperidine oxalate Chemical Properties |
| storage temp. | Store at RT | | solubility | Soluble to 100 mM in DMSO and to 20 mM in ethanol | | form | Powder | | color | White to off-white |
| | 4-(4-Fluorobenzoyl)-1-(4-phenylbutyl)piperidine oxalate Usage And Synthesis |
| Uses | 4F 4PP oxalate is a selective SR-2A antagonist. | | Biological Activity | A selective 5-HT 2A antagonist with almost as high affinity (K i = 5.3 nM) as ketanserin but with a much lower affinity for 5-HT 2C sites (K i = 620 nM). | | in vivo | 4F 4PP (100 nM) reduces the lowest [D-ala2,N-me-phe4,gly.l5]-enkephalin (DAMGO) concentration and can produce a significant depression of evoked field potentials[1]. | | IC 50 | 5-HT2A Receptor: 5.3 nM (Ki); 5-HT2C Receptor: 620 nM (Ki) | | storage | Store at RT |
| | 4-(4-Fluorobenzoyl)-1-(4-phenylbutyl)piperidine oxalate Preparation Products And Raw materials |
|