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| | Orexin A (17-33) Basic information |
| Product Name: | Orexin A (17-33) | | Synonyms: | Orexin A (17-33);OXA (17-33);L-Leucinamide, L-tyrosyl-L-α-glutamyl-L-leucyl-L-leucyl-L-histidylglycyl-L-alanylglycyl-L-asparaginyl-L-histidyl-L-alanyl-L-alanylglycyl-L-isoleucyl-L-leucyl-L-threonyl-;Orexin-A (Human, 17-33) (0.1mg vial) | | CAS: | 343268-91-7 | | MF: | C79H125N23O22 | | MW: | 1748.9787 | | EINECS: | | | Product Categories: | | | Mol File: | 343268-91-7.mol |  |
| | Orexin A (17-33) Chemical Properties |
| Boiling point | 2099.4±65.0 °C(Predicted) | | density | 1.287±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | form | Powder | | pka | 4.42±0.10(Predicted) | | color | White to off-white | | Water Solubility | Soluble to 1 mg/ml in water | | Sequence | Tyr-Glu-Leu-Leu-His-Gly-Ala-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Leu-NH2 |
| | Orexin A (17-33) Usage And Synthesis |
| Uses | OXA(17-33) is a potent and selective orexin-1 receptor (OX1) agonist. OXA(17-33) shows a ～23-fold selectivity for the OX1 (EC50=8.29 nM) over OX2 (187 nM)[1]. | | IC 50 | OX1: 8.29 nM (EC50); OX2: 187 nM (EC50) | | storage | Store at -20°C | | References | [1] German NA, et al. Truncated Orexin Peptides: Structure-Activity Relationship Studies. ACS Med Chem Lett. 2013;4(12):1224-1227. DOI:10.1021/ml400333a |
| | Orexin A (17-33) Preparation Products And Raw materials |
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