- Olmesartan
-
-
2026-06-30
- CAS:144689-24-7
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 1000kgs
- Olmesartan
-
-
2023-04-17
- CAS:144689-24-7
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 100ton
- Olmesartan
-
- $15.00
-
2021-07-09
- CAS:144689-24-7
- Min. Order: 1KG
- Purity: 99%+ HPLC
|
| | Olmesartan Basic information |
| | Olmesartan Chemical Properties |
| Melting point | 186-188°C | | Boiling point | 738.3±70.0 °C(Predicted) | | density | 1.33 | | storage temp. | 2-8°C | | solubility | DMSO (Slightly), Methanol (Slightly, Heated) | | pka | 2.39±0.50(Predicted) | | form | powder | | color | white to beige | | Stability: | Hygroscopic | | InChIKey | VTRAEEWXHOVJFV-UHFFFAOYSA-N | | SMILES | C1(CCC)N(CC2=CC=C(C3=CC=CC=C3C3=NNN=N3)C=C2)C(C(O)=O)=C(C(O)(C)C)N=1 | | CAS DataBase Reference | 144689-24-7(CAS DataBase Reference) |
| | Olmesartan Usage And Synthesis |
| Chemical Properties | White Solid | | Uses | An labelled angiotensin II receptor antagonist. Used as an anti-hypertensive | | Uses | Angiotensin II inhibitor, antihypertensive | | Uses | An angiotensin II (AT1) receptor antagonist | | Uses | Olmesartan Acid (Olmesartan EP Impurity A) is an angiotensin II receptor antagonist. Used as an anti-hypertensive. | | Definition | ChEBI: Olmesartan is a biphenylyltetrazole. It has a role as an antihypertensive agent and an angiotensin receptor antagonist. | | General Description | Olmesartan medoxomil, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl-5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylate (Benicar, Olmetec) uses the tetrazolering system as its acidic system, which participates inreceptor binding.When administered to a patient, the drugis rapidly and completely bioactivated by ester hydrolysis ofthe medoxomil during absorption from the gastrointestinaltract. Once the prodrug is converted to the active form, virtuallyno further metabolism occurs. In September 2007, theFood and Drug Administration (FDA) approved its use as acombination product with the calcium channel blocker amlodipinefor the management of hypertension. This combinationproduct is sold under the tradename of Azor. | | Biochem/physiol Actions | Olmesartan possesses anti-inflammatory and anti-oxidative stress properties. It protects neuronal cells against oligomerized amyloid β (Aβ)-induced cellular senescence. | | storage | Store at +4°C |
| | Olmesartan Preparation Products And Raw materials |
|