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| | HUMAN IL-10 Basic information |
| Product Name: | HUMAN IL-10 | | Synonyms: | RHIL-10;RHIL-1ALPHA;RHIL-1ALPHA-RHIL-1BETA-RHIL-10;RHIL-1BETA;REC INTERLEUKIN-10 (HUMAN);REC IL-10 (HUMAN);RECOMBINANT HUMAN IL-10;IL-10 | | CAS: | 1924707-97-0 | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![HUMAN IL-10 Structure]() |
| | HUMAN IL-10 Chemical Properties |
| storage temp. | −20°C | | form | lyophilized powder | | biological source | human |
| WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | HUMAN IL-10 Usage And Synthesis |
| Uses | Interleukin-10 (IL-10) human has been used to study the effect of IL-10 on cartilage proteoglycan turnover. It has been used as an antigen to analyse the reactivity patterns of autoantibodies in healthy humans and humans suffering from type 1 diabetes mellitus. | | Biological Activity | Interleukin-10 (IL-10) is an anti-inflammatory protein th at inhibits the expression of proinflammatory cytokines such as IL-1 and tumor necrosis factor-α (TNF-α). Like IL-4, IL-10 enhances humoral immune responses and attenuates cell-mediated immune reactions. It inhibits the production of IFN-γ and antigen-specific proliferation of type-1 T helper cells (Th1). It protects the host tissue from damage during immune responses. The protein has a role in modulating viral immunity. IL-10 enhances cytokine production, natural killer cell proliferation and cytotoxicity in vitro. IL-10 is an immunosuppressive cytokine. It promotes wound repair and functions to resolve inflammation in the central nervous system. IL-10 mediates its signaling function through the interleukin receptors namely, IL-10RA and two IL-10RBs. The expression of IL-10 is regulated by signal transducer and activator of transcription 3 (STAT3) and suppressor of cytokine signaling-3 (SOCS3) ratios. Polymorphisms in the IL-10 gene is implicated in breast cancer. |
| | HUMAN IL-10 Preparation Products And Raw materials |
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