5-methyl-N-[2-[4-[(1,2,2,3,3,4,4,5,5,6,6-undecadeuteriocyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]pyrazine-2-carboxamide
| 中文名称 | 5-methyl-N-[2-[4-[(1,2,2,3,3,4,4,5,5,6,6-undecadeuteriocyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]pyrazine-2-carboxamide |
|---|---|
| 中文同义词 | 格列本脲-D11;[2H11]-格列吡嗪;格列吡嗪-[D11]/精确称量;氘11-格列吡嗪 |
| 英文名称 | 5-methyl-N-[2-[4-[(1,2,2,3,3,4,4,5,5,6,6-undecadeuteriocyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]pyrazine-2-carboxamide |
| 英文同义词 | 5-methyl-N-[2-[4-[(1,2,2,3,3,4,4,5,5,6,6-undecadeuteriocyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]pyrazine-2-carboxamide;[2H11]-Glipizide;Glipizide d11Q: What is Glipizide d11 Q: What is the CAS Number of Glipizide d11 Q: What is the storage condition of Glipizide d11 Q: What are the applications of Glipizide d11;D11-Glipizide |
| CAS号 | 1189426-07-0 |
| 分子式 | C21H16D11N5O4S |
| 分子量 | 456.602959558 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 1189426-07-0.mol |
| 结构式 | ![5-methyl-N-[2-[4-[(1,2,2,3,3,4,4,5,5,6,6-undecadeuteriocyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]pyrazine-2-carboxamide 结构式](CAS/20200331/GIF/1189426-07-0.gif) |
5-methyl-N-[2-[4-[(1,2,2,3,3,4,4,5,5,6,6-undecadeuteriocyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]pyrazine-2-carboxamide 性质
| 储存条件 | Store at -20°C |
|---|---|
| 溶解度 | DMSO：微溶，乙酸乙酯：微溶 |
| 形态 | 固体 |
5-methyl-N-[2-[4-[(1,2,2,3,3,4,4,5,5,6,6-undecadeuteriocyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]pyrazine-2-carboxamide 用途与合成方法
Glipizide-d11 是 Glipizide 的氘代物。Glipizide (CP 2872; K 4024) 是一种有效的、具有口服活性的磺酰脲类抗糖尿病试剂 (anti-diabetic agent)，可用于 2 型糖尿病的研究，但不适用于1 型糖尿病。Glipizide 通过部分阻断郎格汉斯胰岛细胞中 ATP 敏感钾通道 (KATP) 发挥作用。