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| Product Name: | MOUSE IL-3 | | Synonyms: | RMIL-3;RECOMBINANT MOUSE IL-3;IL-3;IL-3, MOUSE;INTERLEUKIN-3, MOUSE;INTERLEUKIN-3, MOUSE, RECOMBINANT, E COLI;INTERLEUKIN-3, MURINE;MURINE P-CELL STIMULATION FACTOR | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | monoclonal antibody;cytokine | | Mol File: | Mol File | ![MOUSE IL-3 Structure]() |
| | MOUSE IL-3 Chemical Properties |
| storage temp. | −20°C | | form | lyophilized powder | | color | white to yellow | | biological source | mouse |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | HS Code | 3504009000 | | Storage Class | 11 - Combustible Solids |
| | MOUSE IL-3 Usage And Synthesis |
| Uses | Interleukin-3 from mouse has been used for the determination of 5-lipoxygenase product leukotriene C4 (LTC4) formation. It has also been used as a component of RPMI 1640 medium for cell transfection. | | General Description | Interleukin-3 is a hematopoietic growth factor, which stimulates basophil development and triggers histamine, IL-4 and IL-6 release. It improves monocyte and macrophage activation and phagocytosis, enhances the secretory function of eosinophils. Interleukin-3 promotes endothelial cell proliferation and migration. | | Biochem/physiol Actions | Interleukin-3 (IL-3) is a multifunctional protein, originally called colony forming unit-stimulating activity (CFU-SA), and is produced by activated T lymphocytes. IL-3 supports the formation of multilineage colonies in the early development of multipotent hematopoietic progenitor cells. IL-3 has been shown to induce colony formation of macrophages, neutrophils, mast cells, and megakaryocytes from agar-suspended bone marrow cells. IL-3 also interacts with IL-2 to stimulate growth of T lymphocytes and to induce IgG secretion from activated B cells. Other synonyms for IL-3 include pan-specific hemopoietin, multicolony stimulating factor, mast cell growth factor, burst promoting activity, histamine-producing cell stimulating factor, P cell stimulating factor, and WEHI-3 factor. | | Description | Interleukin-3 mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 135 amino acids and having a molecular mass of 15100 Dalton.
The IL-3 is purified by proprietary chromatographic techniques. | | Source | Escherichia Coli | | Background | Interleukin-3 is a pleiotropic cytokine produced primarily by activated T cells.
IL-3 is thought to function via specific cell surface receptors to stimulate the proliferation, differentiation and survival of haematopoietic cell lines. IL-3 has also been shown to affect the functional activity of a variety of other cell types including mast cells, eosinophils, megakaryocytes and basophils. |
| | MOUSE IL-3 Preparation Products And Raw materials |
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